TOS-PEG5-THP

Base Information

Chemical Name:TOS-PEG5-THP
CAS No.:86259-89-4
Molecular Formula:C20H32O8S
Molecular Weight:432.535
Hs Code.:
Mol file:86259-89-4.mol

Synonyms:monotetrahydropyranyl tetraethylene glycol monotosylate;1-tosyl-13-(tetrahydropyran-2-yl)-1,4,7,10,13-pentaoxatridecane;1-(4-Toluenesulfonyl)-13-(tetrahydropyran-2-yl)-1,4,7,10,13-pentaoxatridecane;2-(1-tosyloxy-3,6,9-trioxaundecan-11-oxy)tetrahydropyran;1-tetrahydropyranyloxy-11-tosyloxy-3,6,9-trioxaundecane;Toluene-4-sulfonic acid 2-(2-{2-[2-(tetrahydro-pyran-2-yloxy)-ethoxy]-ethoxy}-ethoxy)-ethyl ester;1-tosyloxy-11-(tetrahydropyran-2-yloxy)-3,6,9-trioxaundecane;

Suppliers and Price of TOS-PEG5-THP

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

A1 Biochem Labs
Ethanol,2-[2-[2-[2-[(tetrahydro-2H-pyran-2-yl)oxy]ethoxy]ethoxy]ethoxy]-,1-(4-methylbenzenesulfonate) 95%
1 g
$ 350.00

Activate Scientific
Tos-PEG4-THP 97%
5 g
$ 820.00

Apolloscientific
THP-PEG5-Tos
1g
$ 740.00

BroadPharm
THP-PEG5-Tos 98%
5 G
$ 1200.00

BroadPharm
THP-PEG5-Tos 98%
10 G
$ 1800.00

Matrix Scientific
Ethanol
5g
$ 1320.00

Matrix Scientific
Toluene-4-sulfonic acid 2-(2-{2-[2-(tetrahydropyran-2-yloxy)-ethoxy]-ethoxy}-ethoxy)-ethyl ester 95%
5g
$ 1733.00

Matrix Scientific
Toluene-4-sulfonic acid 2-(2-{2-[2-(tetrahydropyran-2-yloxy)-ethoxy]-ethoxy}-ethoxy)-ethyl ester 95%
1g
$ 826.00

Total 8 raw suppliers

Chemical Property of TOS-PEG5-THP

Chemical Property:

PSA：97.90000
LogP:3.37410

Purity/Quality:

99.3% ^*data from raw suppliers

Ethanol,2-[2-[2-[2-[(tetrahydro-2H-pyran-2-yl)oxy]ethoxy]ethoxy]ethoxy]-,1-(4-methylbenzenesulfonate) 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of TOS-PEG5-THP

There total 6 articles about TOS-PEG5-THP which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.3%

: 110-87-2
3,4-dihydro-2H-pyran

: 77544-60-6
p-toluenesulfonic acid 2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethyl ester

: 86259-89-4
2-(2-(2-(2-((tetrahydro-2H-pyran-2-yl)oxy)ethoxy)ethoxy)ethoxy)ethyl 4-methylbenzenesulfonate

Guidance literature:: With toluene-4-sulfonic acid; In tetrahydrofuran; at 20 ℃; for 36h; Inert atmosphere;
DOI:10.1016/j.tetlet.2014.04.066

Reference yield: 85.0%

: 128660-97-9
2-(2-(2-(2-((tetrahydro-2H-pyran-2-yl)oxy)ethoxy)ethoxy)ethoxy)ethan-1-ol

: 98-59-9
p-toluenesulfonyl chloride

: 86259-89-4
2-(2-(2-(2-((tetrahydro-2H-pyran-2-yl)oxy)ethoxy)ethoxy)ethoxy)ethyl 4-methylbenzenesulfonate

Guidance literature:: With triethylamine; In dichloromethane; at 0 - 22 ℃; for 24.25h;

Reference yield:

: 110-87-2
3,4-dihydro-2H-pyran

: 112-60-7
Tetraethylene glycol

: 98-59-9
p-toluenesulfonyl chloride

: O(CH₂CH₂O)4(CH(CH₂)4O)2

: 86259-89-4
2-(2-(2-(2-((tetrahydro-2H-pyran-2-yl)oxy)ethoxy)ethoxy)ethoxy)ethyl 4-methylbenzenesulfonate

Guidance literature:: 3,4-dihydro-2H-pyran; Tetraethylene glycol; With toluene-4-sulfonic acid; In dichloromethane; at 20 ℃; for 24h; Inert atmosphere;

p-toluenesulfonyl chloride; With potassium hydroxide; In tetrahydrofuran; water; at 0 - 20 ℃; Overall yield = 285 g; Inert atmosphere;
DOI:10.1016/j.tetlet.2014.04.066