5,10,15-tris(3,5-di-tert-butylphenyl)-20-formylporphyrin

Base Information

• Chemical Name: 5,10,15-tris(3,5-di-tert-butylphenyl)-20-formylporphyrin
• CAS No.: 625080-10-6
• Molecular Formula: C₆₃H₇₂N₄NiO
• Molecular Weight: 959.981
• Mol file: 625080-10-6.mol

Synonyms:5,10,15-tris(3,5-di-tert-butylphenyl)-20-formylporphyrin

Chemical Property of 5,10,15-tris(3,5-di-tert-butylphenyl)-20-formylporphyrin

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5,10,15-tris(3,5-di-tert-butylphenyl)-20-formylporphyrin

There total 4 articles about 5,10,15-tris(3,5-di-tert-butylphenyl)-20-formylporphyrin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

[5,10,15-tris(3,5-di-tert-butylphenyl)porphyrinato]nickel(II) (262424-39-5) + sodium acetate (127-09-3) → 5,10,15-tris(3,5-di-tert-butylphenyl)-20-formylporphyrin (625080-10-6)

Guidance literature:

With trichlorophosphate; In water; 1,2-dichloro-ethane; N,N-dimethyl-formamide; POCl3 added dropwise to DMF at 0°C, stirred for 30 min at room temp., metal complex in 1,2-dichloroethene poured at 60°C, stirred for 1 h, treated dropwise with aq.NaCH3COO, stirred for 2 h; extd.(CHCl3), washed (H2O), dried (Na2SO4), evapd., chromy.(SiO2-30%CHCl3/hexane);

DOI:10.1021/jp035412j

Reference yield:

C62H71IN4Ni (1639159-76-4) → C63H72N4NiO (625080-10-6)

Guidance literature:

Multi-step reaction with 2 steps

1.1: lithium chloride; isopropyl chloride / ethylene dibromide; tetrahydrofuran / 12 h / 20 °C / Inert atmosphere

1.2: 2 h / -40 °C / Inert atmosphere; Schlenk technique

2.1: tetrahydrofuran / 24 h / 20 °C / Inert atmosphere; Schlenk technique

With isopropyl chloride; lithium chloride; In tetrahydrofuran; ethylene dibromide;

DOI:10.1002/ejoc.201402391

Reference yield:

C62H72MgN4Ni + N,N-dimethyl-formamide (68-12-2,33513-42-7) → C63H72N4NiO (625080-10-6)

Guidance literature:

In tetrahydrofuran; at 20 ℃; for 24h; Inert atmosphere; Schlenk technique;

DOI:10.1002/ejoc.201402391

upstream raw materials:

[5,10,15-tris(3,5-di-tert-butylphenyl)porphyrinato]nickel(II)

sodium acetate

N,N-dimethyl-formamide

C₆₂H₇₁IN₄Ni