Dithiophosphoric acid O-[(2R,3S,5R)-5-(3-benzoyl-5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-2-hydroxymethyl-tetrahydro-furan-3-yl] ester S,S'-diphenyl ester

Base Information

Chemical Name:Dithiophosphoric acid O-[(2R,3S,5R)-5-(3-benzoyl-5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-2-hydroxymethyl-tetrahydro-furan-3-yl] ester S,S'-diphenyl ester
CAS No.:94189-78-3
Molecular Formula:C₂₉H₂₇N₂O₇PS₂
Molecular Weight:610.648
Hs Code.:

Dithiophosphoric acid O-[(2R,3S,5R)-5-(3-benzoyl-5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-2-hydroxymethyl-tetrahydro-furan-3-yl] ester S,S'-diphenyl ester

Synonyms:Dithiophosphoric acid O-[(2R,3S,5R)-5-(3-benzoyl-5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-2-hydroxymethyl-tetrahydro-furan-3-yl] ester S,S'-diphenyl ester

Suppliers and Price of Dithiophosphoric acid O-[(2R,3S,5R)-5-(3-benzoyl-5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-2-hydroxymethyl-tetrahydro-furan-3-yl] ester S,S'-diphenyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Dithiophosphoric acid O-[(2R,3S,5R)-5-(3-benzoyl-5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-2-hydroxymethyl-tetrahydro-furan-3-yl] ester S,S'-diphenyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Dithiophosphoric acid O-[(2R,3S,5R)-5-(3-benzoyl-5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-2-hydroxymethyl-tetrahydro-furan-3-yl] ester S,S'-diphenyl ester

There total 7 articles about Dithiophosphoric acid O-[(2R,3S,5R)-5-(3-benzoyl-5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-2-hydroxymethyl-tetrahydro-furan-3-yl] ester S,S'-diphenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 94219-34-8
Dithiophosphoric acid O-{(2R,3S,5R)-5-(3-benzoyl-5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-tetrahydro-furan-3-yl} ester S,S'-diphenyl ester

: 94189-78-3
Dithiophosphoric acid O-[(2R,3S,5R)-5-(3-benzoyl-5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-2-hydroxymethyl-tetrahydro-furan-3-yl] ester S,S'-diphenyl ester

Guidance literature:: With trifluoroacetic acid; In chloroform; at 0 ℃; for 0.0833333h;
DOI:10.1016/0040-4039(84)80055-6

Reference yield:

: 106502-50-5
3-Benzoyl-1-{(2R,4S,5R)-4-hydroxy-5-[(3-imidazol-1-ylmethyl-phenyl)-bis-(4-methoxy-phenyl)-methoxymethyl]-tetrahydro-furan-2-yl}-5-methyl-1H-pyrimidine-2,4-dione

: 94189-78-3
Dithiophosphoric acid O-[(2R,3S,5R)-5-(3-benzoyl-5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-2-hydroxymethyl-tetrahydro-furan-3-yl] ester S,S'-diphenyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: mesitylenedisulfonyl chloride (MDS) / 0.17 h

2: 0.2 M dichloroacetic acid / CH₂Cl₂ / 0.01 h / 22 °C

With dichloro-acetic acid; 2,4,6-trimethyl-1,3-benzenedisulfonyl dichloride; In dichloromethane;
DOI:10.1021/jo00381a047

Reference yield:

: 102573-69-3
5'-O-(4-4'-dimethoxytrityl)-N³-benzoyl thymidine

: 94189-78-3
Dithiophosphoric acid O-[(2R,3S,5R)-5-(3-benzoyl-5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-2-hydroxymethyl-tetrahydro-furan-3-yl] ester S,S'-diphenyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 91 percent

2: 86 percent / 2percent CF₃CO₂H / CHCl₃ / 0.08 h / 0 °C

With trifluoroacetic acid; In chloroform;
DOI:10.1016/0040-4039(84)80055-6