C₃₀H₄₅N₃O₁₄S₂

Base Information

• Chemical Name: C₃₀H₄₅N₃O₁₄S₂
• CAS No.: 1415712-81-0
• Molecular Formula: C₃₀H₄₅N₃O₁₄S₂
• Molecular Weight: 735.831
• Mol file: 1415712-81-0.mol

Synonyms:C₃₀H₄₅N₃O₁₄S₂

Chemical Property of C₃₀H₄₅N₃O₁₄S₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₀H₄₅N₃O₁₄S₂

There total 9 articles about C₃₀H₄₅N₃O₁₄S₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

C30H45N3O12S2 (1415712-79-6) → C30H45N3O14S2 (1415712-81-0)

Guidance literature:

With potassium permanganate; In water; acetic acid; at -15 - -10 ℃; for 1h; Inert atmosphere;

DOI:10.1016/j.tet.2011.10.100

Reference yield:

2-(2-(2-aminoethoxy)ethoxy)ethan-1-ol (6338-55-2) → C30H45N3O14S2 (1415712-81-0)

Guidance literature:

Multi-step reaction with 5 steps

1.1: sodium hydrogencarbonate / water; acetonitrile / 2 h / 0 - 20 °C / Inert atmosphere

2.1: potassium hydrogencarbonate / acetonitrile / 72 h / 80 °C / Inert atmosphere

3.1: sodium iodide / acetone / 20 h / 20 °C / Inert atmosphere

3.2: polymer-supported triphenylphosphine / 1.67 h / 0 - 20 °C / Inert atmosphere

3.3: 4.17 h / 0 - 20 °C / Inert atmosphere

4.1: triethylamine / dichloromethane / 0.17 h / 0 °C / Inert atmosphere

4.2: 0.83 h / 0 - 20 °C / Inert atmosphere

5.1: potassium permanganate / water; acetic acid / 1 h / -15 - -10 °C / Inert atmosphere

With potassium permanganate; sodium hydrogencarbonate; potassium hydrogencarbonate; triethylamine; sodium iodide; In dichloromethane; water; acetic acid; acetone; acetonitrile; 2.1: |Michael Addition;

DOI:10.1016/j.tet.2011.10.100

Reference yield:

Chloromethyl pivalate (18997-19-8) → C30H45N3O14S2 (1415712-81-0)

Guidance literature:

Multi-step reaction with 3 steps

1.1: triethylamine / N,N-dimethyl-formamide / 0.5 h / Inert atmosphere

1.2: 4 h / 25 °C / Inert atmosphere

2.1: triethylamine / dichloromethane / 0.17 h / 0 °C / Inert atmosphere

2.2: 0.83 h / 0 - 20 °C / Inert atmosphere

3.1: potassium permanganate / water; acetic acid / 1 h / -15 - -10 °C / Inert atmosphere

With potassium permanganate; triethylamine; In dichloromethane; water; acetic acid; N,N-dimethyl-formamide;

DOI:10.1016/j.tet.2011.10.100

upstream raw materials:

Chloromethyl pivalate

(2S,5R,6R)-2-[(2,2-dimethylpropanoyl)oxy]-methylpenicillanat-6-aminium 4-methylbenzenesulfonate

C₃₀H₄₅N₃O₁₂S₂

2-[2-{2-(N-benzyloxycarbonyl)aminoethoxy}ethoxy]ethanol