n3-[3-methoxy-4-(4-methyl-imidazol-1-yl)-phenyl]-5-propylamino-1H-[1,2,4]triazole-3-amine

Base Information

Chemical Name:n3-[3-methoxy-4-(4-methyl-imidazol-1-yl)-phenyl]-5-propylamino-1H-[1,2,4]triazole-3-amine
CAS No.:1319068-30-8
Molecular Formula:C₁₆H₂₁N₇O
Molecular Weight:327.389
Hs Code.:

Synonyms:n3-[3-methoxy-4-(4-methyl-imidazol-1-yl)-phenyl]-5-propylamino-1H-[1,2,4]triazole-3-amine

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Chemical Property of n3-[3-methoxy-4-(4-methyl-imidazol-1-yl)-phenyl]-5-propylamino-1H-[1,2,4]triazole-3-amine

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Technology Process of n3-[3-methoxy-4-(4-methyl-imidazol-1-yl)-phenyl]-5-propylamino-1H-[1,2,4]triazole-3-amine

There total 4 articles about n3-[3-methoxy-4-(4-methyl-imidazol-1-yl)-phenyl]-5-propylamino-1H-[1,2,4]triazole-3-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 37.0%

: 1319067-61-2
N₃-[3-methoxy-4-(4-methyl-imidazol-1-yl)-phenyl]-1H-[1,2,4]triazole-3,5-diamine

: 123-38-6
propionaldehyde

: 1319068-30-8
n3-[3-methoxy-4-(4-methyl-imidazol-1-yl)-phenyl]-5-propylamino-1H-[1,2,4]triazole-3-amine

Guidance literature:: With sodium tetrahydroborate; acetic acid; In tetrahydrofuran; ethanol; at 20 ℃; Inert atmosphere;

Reference yield: 37.0%

: 1319067-61-2
N₃-[3-methoxy-4-(4-methyl-imidazol-1-yl)-phenyl]-1H-[1,2,4]triazole-3,5-diamine

: 123-72-8
butyraldehyde

: 1319068-30-8
n3-[3-methoxy-4-(4-methyl-imidazol-1-yl)-phenyl]-5-propylamino-1H-[1,2,4]triazole-3-amine

Guidance literature:: N₃-[3-methoxy-4-(4-methyl-imidazol-1-yl)-phenyl]-1H-[1,2,4]triazole-3,5-diamine; butyraldehyde; With sodium tetrahydroborate; acetic acid; In tetrahydrofuran; ethanol; at 20 ℃; Inert atmosphere;

With sodium hydroxide; In tetrahydrofuran; ethanol; water;

Reference yield:

: 958245-18-6
3-methoxy-4-(4-methyl-1H-imidazol-1-yl)aniline

: 1319068-30-8
n3-[3-methoxy-4-(4-methyl-imidazol-1-yl)-phenyl]-5-propylamino-1H-[1,2,4]triazole-3-amine

Guidance literature:: Multi-step reaction with 3 steps

1: isopropyl alcohol / 2 h / 20 °C

2: hydrazine hydrate / methanol / 1 h / 20 °C

3: sodium tetrahydroborate; acetic acid / ethanol; tetrahydrofuran / 20 °C / Inert atmosphere

With sodium tetrahydroborate; hydrazine hydrate; acetic acid; In tetrahydrofuran; methanol; ethanol; isopropyl alcohol;