4-bromo-2-(4-bromo-3-fluorophenyl)-5-ethyltetrahydropyran

Base Information

• Chemical Name: 4-bromo-2-(4-bromo-3-fluorophenyl)-5-ethyltetrahydropyran
• CAS No.: 1337991-98-6
• Molecular Formula: C₁₃H₁₅Br₂FO
• Molecular Weight: 366.068
• Mol file: 1337991-98-6.mol

Synonyms:4-bromo-2-(4-bromo-3-fluorophenyl)-5-ethyltetrahydropyran

Chemical Property of 4-bromo-2-(4-bromo-3-fluorophenyl)-5-ethyltetrahydropyran

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 4-bromo-2-(4-bromo-3-fluorophenyl)-5-ethyltetrahydropyran

There total 1 articles about 4-bromo-2-(4-bromo-3-fluorophenyl)-5-ethyltetrahydropyran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-ethylbut-3-en-1-ol (53045-70-8) + bismuth(III) bromide + 4-bromo-3-fluorobenzaldehyde (133059-43-5) → 4-bromo-2-(4-bromo-3-fluorophenyl)-5-ethyltetrahydropyran (1337991-98-6)

Guidance literature:

With hydrogenchloride; sodium sulfate; In toluene;

Reference yield:

[1,1'-bis(diphenylphosphine)ferrocene]-palladium(II) chloride + 4-bromo-2-(4-bromo-3-fluorophenyl)-5-ethyltetrahydropyran (1337991-98-6) + bis(pinacol)diborane (73183-34-3) → 4-bromo-5-ethyl-2-[3-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]tetrahydropyran (1337991-99-7)

Guidance literature:

With potassium acetate; sodium sulfate; In toluene;

upstream raw materials:

2-ethylbut-3-en-1-ol

4-bromo-3-fluorobenzaldehyde

Downstream raw materials:

4-bromo-5-ethyl-2-[3-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]tetrahydropyran