Chemical Property of Dithizone
Chemical Property:
- Appearance/Colour:dark brown or black crystals
- Vapor Pressure:0mmHg at 25°C
- Melting Point:168°C (dec.)
- Refractive Index:1.648
- Boiling Point:376.1 °C at 760 mmHg
- PKA:pK1:4.50;pK2:15 (25°C)
- Flash Point:181.2 °C
- PSA：80.87000
- Density:1.2 g/cm3
- LogP:4.13580
- Storage Temp.:Store at room temperature.
- Solubility.:Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
- Water Solubility.:Soluble in ethanol, chloroform, dimethylsulfoxide, and pyridine. Insoluble in water.
- XLogP3:4.2
- Hydrogen Bond Donor Count:2
- Hydrogen Bond Acceptor Count:3
- Rotatable Bond Count:3
- Exact Mass:256.07826757
- Heavy Atom Count:18
- Complexity:281
- Purity/Quality:
-
99%, *data from raw suppliers
Dithizone *data from reagent suppliers
Safty Information:
- Pictogram(s):
Xi
- Hazard Codes:Xi
- Statements:
22-36/37/38
- Safety Statements:
36-26
- MSDS Files:
-
SDS file from LookChem
Useful:
- Chemical Classes:Other Classes -> Thiourea Compounds
- Canonical SMILES:C1=CC=C(C=C1)NNC(=S)N=NC2=CC=CC=C2
-
Uses
Dithizone is an organosulfur compound that acts as a chelating agent and forms complexes with metals such as lead and mercury. Dithizone is used to assess the purity of human pancreatic islet preparations used for transplantation into patients with type 1 diabetes. Sensitive reagent for several heavy metals, Co, Cu, Pb, and Hg; especially for the estimation of minute amounts of Pb. Dithizone is used as an indicator for minute amounts of lead. It acts as a chelating agent for heavy metal poisoning. As a ligand, it forms complexes with metals like zinc, lead and mercury. Further, it is used to assess the purity of human pancreatic islet preparations, which is used for transplantation in patients with type 1 diabetes. In addition to this, it is used as a titrant in the quantitative determination of heavy metals.
