147-84-2

Basic information

• Product Name: DIETHANOL-DITHIOCARBAMATE
• Synonyms: DIETHYLDITHIOCARBAMATE;DIETHYLDITHIOCARBAMIC ACID;Ditiocarb;N,N-DIETHYLDITHIOCARBAMATE;DIETHANOL-DITHIOCARBAMATE;N,N-Diethyldithiocarbamicacid;DEDTC;DIECA
• CAS NO: 147-84-2
• Molecular Formula: C₅H₁₁NS₂
• Molecular Weight: 149.28
• EINECS: 205-701-7
• Mol File: 147-84-2.mol
• Article Data: 13

Chemical Properties

• Melting Point: 143-144 °C
• Boiling Point: 176.4°C at 760 mmHg
• Flash Point: 60.5°C
• Appearance: /
• Density: 1.079 (estimate)
• Vapor Pressure: 1.1mmHg at 25°C
• Refractive Index: 1.5300 (estimate)
• PKA: 5.42±0.60(Predicted)
• CAS DataBase Reference: DIETHANOL-DITHIOCARBAMATE(CAS DataBase Reference)
• NIST Chemistry Reference: DIETHANOL-DITHIOCARBAMATE(147-84-2)
• EPA Substance Registry System: DIETHANOL-DITHIOCARBAMATE(147-84-2)

Safety Data

• Hazardous Substances Data: 147-84-2(Hazardous Substances Data)

Usage

Uses

N,N-Diethyldithiocarbamic Acid is a metabolite of Disulfiram (D493640). The acid is a known inhibitor of superoxide dismutase, this agent can either potentiate or protect against cell oxidative damage caused by ionizing radiation

InChI:InChI=1/C5H11NS2.K/c1-3-6(4-2)5(7)8;/h3-4H2,1-2H3,(H,7,8);/q;+1/p-1

Upstream product

• 75-15-0 carbon disulfide 
• 109-89-7 diethylamine 

Downstream Products

• 55393-30-1 3-chloro-1-dicyclohexylamino-5-(diethyl-thiocarbamoylsulfanyl)-1λ⁴-[1,2,4,6]thiatriazine 
• 5347-18-2 2-hydroxyethyl diethyldithiocarbamate 
• 63521-71-1 S-(1,3-diphenyl-3-oxopropen-1-yl)-N,N-diethyldithiocarbamate 
• 686-07-7 methyl diethyldithiocarbamate 
• 75-15-0 carbon disulfide 
• 109-89-7 diethylamine 
• 97-77-8 disulfiram 
• 174281-08-4 [Mo(NC₆H₃Cl₂)2(S₂CN(C₂H₅)2)2] 
• 70749-52-9 [Mo(NC₆H₄CH₃)2(S₂CN(C₂H₅)2)2] 
• 259267-58-8 [Mo(NC₆H₄CH₃)2(S₂CN(C₂H₅)2)2] 
• 174281-06-2 [Mo(NC₆H₄CH₃)2(S₂CN(C₂H₅)2)2] 
• 259267-59-9 [Mo(NC₆H₄F)2(S₂CN(C₂H₅)2)2] 
• 259267-60-2 [Mo(NC₆H₃(CH₃)2)2(S₂CN(C₂H₅)2)2] 
• 259267-61-3 [Mo(NC₆H₃(CH₃)2)2(S₂CN(C₂H₅)2)2] 

Relevant articles and documents

Synthesis of S- and N-functionalized dithiocarbamates from cyclic sulfates

A novel methodology for the synthesis of S- and N-functionalized dithiocarbamates starting from cyclic sulfates, amines and carbon disulfide by using different protocols, including microwave assistance and a multicomponent variant, has been developed. The procedure is highly versatile, simple and efficient. As an efficient route to dithiocarbamates, a simple and versatile method for preparing S- and N-functionalized dithiocarbamates starting for readily available cyclic sulfates and commercial amines under environmentally friendly conditions is reported. Copyright

Visible-Light-Induced Photocatalytic Synthesis of β-Keto Dithiocarbamates via Difunctionalization of Styrenes

A facile photocatalyzed strategy for difunctionalization of styrenes in the presence of CS2 and amines providing β-keto dithiocarbamates has been developed. In the case of 4-nitrostyrene and 2-vinylpyridine, however, only 2-arylethylthiocarbamates are interestingly formed without the aid of photoredox catalysis/TBHP.

PROCHELATORS AS TARGETED PRODRUGS FOR PROSTATE CANCER AND METHODS OF MAKING AND USING SAME

The present disclosure provides prochelators as targeted prodrugs for cancer, such as prostate cancer, and methods of making and using the same.