C₁₆H₂₁Cl₂NO₃

Base Information

Chemical Name:C₁₆H₂₁Cl₂NO₃
CAS No.:1374849-91-8
Molecular Formula:C₁₆H₂₁Cl₂NO₃
Molecular Weight:346.254
Hs Code.:

C<sub>16</sub>H<sub>21</sub>Cl<sub>2</sub>NO<sub>3</sub>

Synonyms:C₁₆H₂₁Cl₂NO₃

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of C₁₆H₂₁Cl₂NO₃

Chemical Property:

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Technology Process of C₁₆H₂₁Cl₂NO₃

There total 1 articles about C₁₆H₂₁Cl₂NO₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 69610-41-9,117625-90-8
Boc-L-Pro-H

: 82297-90-3
3,5-dichlorophenylmagnesium bromide

: 1374849-91-8
C₁₆H₂₁Cl₂NO₃

Guidance literature:: Boc-L-Pro-H; 3,5-dichlorophenylmagnesium bromide; In tetrahydrofuran; at -78 - 20 ℃; for 2.5h; Inert atmosphere;

With water; In tetrahydrofuran;

Reference yield:

: 1374849-91-8
C₁₆H₂₁Cl₂NO₃

: 6160-65-2
1,1'-Thiocarbonyldiimidazole

: 1374849-92-9
C₂₀H₂₃Cl₂N₃O₄

Guidance literature:: In 1,2-dichloro-ethane; at 85 ℃; for 2h; Sealed tube;

Reference yield:

: 1374849-91-8
C₁₆H₂₁Cl₂NO₃

: 1374849-90-7
(S)-(2-(3,5-dichlorobenzyl)pyrrolidin-1-yl)(3-hydroxyquinoxalin-2-yl)methanone

Guidance literature:: Multi-step reaction with 4 steps

1: 1,2-dichloro-ethane / 2 h / 85 °C / Sealed tube

2: tri-n-butyl-tin hydride / 2,2'-azobis(isobutyronitrile) / toluene / 85 °C / Inert atmosphere

3: trifluoroacetic acid / dichloromethane / 2 h / 20 °C

4: N-ethyl-N,N-diisopropylamine; HATU / N,N-dimethyl-formamide / 85 °C

With tri-n-butyl-tin hydride; N-ethyl-N,N-diisopropylamine; HATU; trifluoroacetic acid; 2,2'-azobis(isobutyronitrile); In dichloromethane; 1,2-dichloro-ethane; N,N-dimethyl-formamide; toluene;