1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propan-1-one

Base Information

Chemical Name:1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propan-1-one
CAS No.:1256359-22-4
Molecular Formula:C₁₅H₂₁BO₃
Molecular Weight:260.141
Hs Code.:2931900090
DSSTox Substance ID:DTXSID50682234
Wikidata:Q82606541
Mol file:1256359-22-4.mol

Synonyms:1256359-22-4;1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propan-1-one;4-(Propionyl)phenylboronic acid pinacol ester;1-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]propan-1-one;4-(propanyl)phenylboronic acid pinacol ester;(4-PROPIONYLPHENYL)BORONIC ACID PINACOL ESTER;SCHEMBL14248315;DTXSID50682234;MFCD16036136;AKOS016000628;BS-19906;CS-0175890;F30635;EN300-7390404;Z2044788096;1-[4-(TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENYL]PROPAN-1-ONE

Suppliers and Price of 1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propan-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-(Propionyl)phenylboronicacidpinacolester
25mg
$ 45.00

Crysdot
1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propan-1-one 95+%
5g
$ 734.00

American Custom Chemicals Corporation
1-(4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENYL)PROPAN-1-ONE 95.00%
1G
$ 345.45

Alichem
1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propan-1-one
5g
$ 733.59

AK Scientific
4-(Propionyl)phenylboronicacidpinacolester
250mg
$ 151.00

Total 11 raw suppliers

Chemical Property of 1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propan-1-one

Chemical Property:

Storage Temp.:Room temperature.
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:260.1583747
Heavy Atom Count:19
Complexity:327

Purity/Quality:

97% ^*data from raw suppliers

4-(Propionyl)phenylboronicacidpinacolester ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:B1(OC(C(O1)(C)C)(C)C)C2=CC=C(C=C2)C(=O)CC

Technology Process of 1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propan-1-one

There total 3 articles about 1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.4%

: 10342-83-3
4'-Bromopropiophenone

: 73183-34-3
bis(pinacol)diborane

: 1256359-22-4
1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propan-1-one

Guidance literature:: With potassium acetate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In 1,4-dioxane; at 80 ℃; for 18h; Inert atmosphere;

Reference yield: 60.0%

: 74-85-1
ethene

: 180516-87-4
4-carboxyphenylboronic acid pinacol ester

: 1256359-22-4
1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propan-1-one

Guidance literature:: With (1,2-dimethoxyethane)dichloronickel(II); 5, 6-dimethyl-1,10-phenanthroline; [4,4′-bis(1,1-dimethylethyl)-2,2′-bipyridine-N1,N1′]bis{3,5-difluoro-2-[5-(trifluoromethyl)-2-pyridinyl-κN]phenyl-κC}iridium(III) hexafluorophosphate; N-ethyl-N,N-diisopropylamine; triphenylphosphine; In acetonitrile; at 20 ℃; for 2h; under 760.051 Torr; Irradiation; Inert atmosphere; Sealed tube; Schlenk technique;
DOI:10.1039/d1cc04188f

Reference yield:

: 108-86-1,52753-63-6
bromobenzene

: 1256359-22-4
1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propan-1-one

Guidance literature:: Multi-step reaction with 2 steps

1: aluminum (III) chloride / 2 h / 50 °C

2: potassium acetate / (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / 1,4-dioxane / 18 h / 80 °C / Inert atmosphere

With potassium acetate; aluminum (III) chloride; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In 1,4-dioxane;