3-amino-1-hydroxy-3-methyl-4-phenylbutan-2-one semicarbazone hydrochloride

Base Information

Chemical Name:3-amino-1-hydroxy-3-methyl-4-phenylbutan-2-one semicarbazone hydrochloride
CAS No.:101231-99-6
Molecular Formula:C₁₂H₁₈N₄O₂*ClH
Molecular Weight:286.761
Hs Code.:

Synonyms:3-amino-1-hydroxy-3-methyl-4-phenylbutan-2-one semicarbazone hydrochloride

Suppliers and Price of 3-amino-1-hydroxy-3-methyl-4-phenylbutan-2-one semicarbazone hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of 3-amino-1-hydroxy-3-methyl-4-phenylbutan-2-one semicarbazone hydrochloride

Chemical Property:

Purity/Quality:: 99% ，98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

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Technology Process of 3-amino-1-hydroxy-3-methyl-4-phenylbutan-2-one semicarbazone hydrochloride

There total 8 articles about 3-amino-1-hydroxy-3-methyl-4-phenylbutan-2-one semicarbazone hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 563-41-7
semicarbazide hydrochloride

: 101210-84-8
3-amino-1-hydroxy-3-methyl-4-phenylbutan-2-one hydrochloride

: 101231-99-6
3-amino-1-hydroxy-3-methyl-4-phenylbutan-2-one semicarbazone hydrochloride

Guidance literature:: With sodium hydrogencarbonate; In methanol; water; r.t. water, 1 h then 35 deg C,;

Reference yield:

: 64282-11-7
methyl 2-(phenylmethyl)-2-aminopropionate

: 101231-99-6
3-amino-1-hydroxy-3-methyl-4-phenylbutan-2-one semicarbazone hydrochloride

Guidance literature:: Multi-step reaction with 7 steps

1: 92 percent / diethyl ether / Ambient temperature

2: 98 percent / 1M-sodium hydroxide / H₂O / 1 h / Heating

3: 98 percent / thionyl chloride / 1 h / Heating

4: 58 percent / diethyl ether / Ambient temperature

5: 95 percent / 0.5M-sulphuric acid / dioxane; H₂O / 0.75 h / Heating

6: 98 percent / 1.) hydrazine hydrate, 2.) 0.2M-hydrochloric acid / ethanol / 1.) 2 h, reflux, 2.) r.t. HCl, 5 min reflux

7: 97 percent / sodium hydrogen carbonate / methanol; H₂O / r.t. water, 1 h then 35 deg C,

With hydrogenchloride; sodium hydroxide; thionyl chloride; sulfuric acid; sodium hydrogencarbonate; hydrazine hydrate; In 1,4-dioxane; methanol; diethyl ether; ethanol; water;

Reference yield:

: 101210-78-0
methyl 2-(2-carboxybenzamido)-2-methyl-3-phenylpropanoate

: 101231-99-6
3-amino-1-hydroxy-3-methyl-4-phenylbutan-2-one semicarbazone hydrochloride

Guidance literature:: Multi-step reaction with 6 steps

1: 98 percent / 1M-sodium hydroxide / H₂O / 1 h / Heating

2: 98 percent / thionyl chloride / 1 h / Heating

3: 58 percent / diethyl ether / Ambient temperature

4: 95 percent / 0.5M-sulphuric acid / dioxane; H₂O / 0.75 h / Heating

5: 98 percent / 1.) hydrazine hydrate, 2.) 0.2M-hydrochloric acid / ethanol / 1.) 2 h, reflux, 2.) r.t. HCl, 5 min reflux

6: 97 percent / sodium hydrogen carbonate / methanol; H₂O / r.t. water, 1 h then 35 deg C,

With hydrogenchloride; sodium hydroxide; thionyl chloride; sulfuric acid; sodium hydrogencarbonate; hydrazine hydrate; In 1,4-dioxane; methanol; diethyl ether; ethanol; water;