N'-<4--N-methylamino>benzoyl>-L-glutamic acid γ-hydrazide

Base Information

Chemical Name:N'-<4--N-methylamino>benzoyl>-L-glutamic acid γ-hydrazide
CAS No.:79640-75-8
Molecular Formula:C₂₀H₂₄N₁₀O₄
Molecular Weight:468.475
Hs Code.:

N'-<4-<N-<(2,4-diamino-6-pteridinyl)methyl>-N-methylamino>benzoyl>-L-glutamic acid γ-hydrazide

Synonyms:N'-<4--N-methylamino>benzoyl>-L-glutamic acid γ-hydrazide

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Chemical Property of N'-<4--N-methylamino>benzoyl>-L-glutamic acid γ-hydrazide

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Technology Process of N'-<4--N-methylamino>benzoyl>-L-glutamic acid γ-hydrazide

There total 6 articles about N'-<4--N-methylamino>benzoyl>-L-glutamic acid γ-hydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 67022-39-3
γ-methyl N'-<4--N-methylamino>benzoyl>-L-glutamate

: 79640-75-8
N'-<4--N-methylamino>benzoyl>-L-glutamic acid γ-hydrazide

Guidance literature:: With hydrazine hydrate; In methanol; for 48h; Ambient temperature;
DOI:10.1021/jm00131a003

Reference yield: 45.0%

: 79640-69-0
tert-butyl N'-<4--N-methylamino>benzoyl>-L-glutamic acid γ-hydrazide

: 79640-75-8
N'-<4--N-methylamino>benzoyl>-L-glutamic acid γ-hydrazide

Guidance literature:: With hydrogenchloride; for 1h;
DOI:10.1021/jm00144a016

Reference yield:

: 59-05-2
N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid

: 79640-75-8
N'-<4--N-methylamino>benzoyl>-L-glutamic acid γ-hydrazide

Guidance literature:: Multi-step reaction with 2 steps

1: 73 percent / sodium sulfate / tetrafluoroboric acid etherate / 18 h / Ambient temperature

2: 91 percent / N₂H₄*H₂O / methanol / 48 h / Ambient temperature

With hydrazine hydrate; sodium sulfate; tetrafluoroboric acid diethyl ether; In methanol;
DOI:10.1021/jm00131a003