benzyl 2-(benzyloxy)-4-(N-(4-cyclohexylbenzyl)-2-(methylamino)-acetamido)benzoate

Base Information

Chemical Name:benzyl 2-(benzyloxy)-4-(N-(4-cyclohexylbenzyl)-2-(methylamino)-acetamido)benzoate
CAS No.:1334493-20-7
Molecular Formula:C₃₇H₄₀N₂O₄
Molecular Weight:576.736
Hs Code.:

Synonyms:benzyl 2-(benzyloxy)-4-(N-(4-cyclohexylbenzyl)-2-(methylamino)-acetamido)benzoate

Suppliers and Price of benzyl 2-(benzyloxy)-4-(N-(4-cyclohexylbenzyl)-2-(methylamino)-acetamido)benzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of benzyl 2-(benzyloxy)-4-(N-(4-cyclohexylbenzyl)-2-(methylamino)-acetamido)benzoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of benzyl 2-(benzyloxy)-4-(N-(4-cyclohexylbenzyl)-2-(methylamino)-acetamido)benzoate

There total 8 articles about benzyl 2-(benzyloxy)-4-(N-(4-cyclohexylbenzyl)-2-(methylamino)-acetamido)benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 1334493-18-3
benzyl 2-(benzyloxy)-4-(N-(4-cyclohexylbenzyl)-2-(2,2,2-trifluoro-N-methylacetamido)acetamido)benzoate

: 1334493-20-7
benzyl 2-(benzyloxy)-4-(N-(4-cyclohexylbenzyl)-2-(methylamino)-acetamido)benzoate

Guidance literature:: With lithium hydroxide monohydrate; In tetrahydrofuran; water; at 20 ℃; for 0.166667h; Inert atmosphere;
DOI:10.1016/j.bmcl.2011.06.056

Reference yield:

: benzyl 4-(2-((((9H-fluoren-9-yl)methoxy)carbonyl)(methyl)amino)-N-(4-cyclohexylbenzyl)acetamido)-2-(benzyloxy)benzoate

: 1334493-20-7
benzyl 2-(benzyloxy)-4-(N-(4-cyclohexylbenzyl)-2-(methylamino)-acetamido)benzoate

Guidance literature:: With piperidine; In dichloromethane; at 0 ℃; for 0.5h; Inert atmosphere;
DOI:10.1021/acsmedchemlett.7b00544

Reference yield:

: 1241832-99-4
benzyl 4-amino-2-(benzyloxy)benzoate

: 1334493-20-7
benzyl 2-(benzyloxy)-4-(N-(4-cyclohexylbenzyl)-2-(methylamino)-acetamido)benzoate

Guidance literature:: Multi-step reaction with 4 steps

1: acetic acid / methanol / 3 h / 45 °C / Inert atmosphere; Molecular sieve

2: sodium cyanoborohydride / methanol / 20 °C / Inert atmosphere

3: dichlorotriphenylphosphorane / chloroform / 12 h / 60 °C / Inert atmosphere

4: lithium hydroxide monohydrate / tetrahydrofuran; water / 0.17 h / 20 °C / Inert atmosphere

With lithium hydroxide monohydrate; sodium cyanoborohydride; acetic acid; dichlorotriphenylphosphorane; In tetrahydrofuran; methanol; chloroform; water;
DOI:10.1016/j.bmcl.2011.06.056