(R)-2-Hydroxy-4-(methylthio)butyric acid

Base Information

Chemical Name:(R)-2-Hydroxy-4-(methylthio)butyric acid
CAS No.:39638-34-1
Molecular Formula:C5H10 O3 S
Molecular Weight:150.199
Hs Code.:
European Community (EC) Number:254-555-0
UNII:YC5J89UM94
DSSTox Substance ID:DTXSID201266605
Nikkaji Number:J261.409J
Mol file:39638-34-1.mol

Synonyms:39638-34-1;(R)-2-Hydroxy-4-(methylthio)butyric acid;Desmeninol, (R)-;YC5J89UM94;EINECS 254-555-0;UNII-YC5J89UM94;(2R)-2-hydroxy-4-methylsulfanylbutanoic acid;Butanoic acid,2-hydroxy-4-(methylthio)-, (2R)-;4-methylsulfanyl-2-oxidanyl-butanoic acid;(2R)-2-Hydroxy-4-(methylthio)butanoic acid;SCHEMBL9331726;ONFOSYPQQXJWGS-SCSAIBSYSA-N;DTXSID201266605;(R)-2-Hydroxy-4-(methylthio) butyric Acid;D-2-HYDROXY-4-METHYLMERCAPTOBUTYRIC ACID;Butanoic acid, 2-hydroxy-4-(methylthio)-, (2R)-;D-2-HYDROXY-4-(METHYLMERCAPTO)BUTANOIC ACID;BUTANOIC ACID, 2-HYDROXY-4-(METHYLTHIO)-, (R)-;H9L

Suppliers and Price of (R)-2-Hydroxy-4-(methylthio)butyric acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of (R)-2-Hydroxy-4-(methylthio)butyric acid

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:316.5°Cat760mmHg
Flash Point:145.2°C
PSA：82.83000
Density:1.277g/cm³
LogP:0.18500
XLogP3:0.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:150.03506535
Heavy Atom Count:9
Complexity:94.2

Purity/Quality:: 98%Min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CSCCC(C(=O)O)O
Isomeric SMILES:CSCC[C@H](C(=O)O)O

Technology Process of (R)-2-Hydroxy-4-(methylthio)butyric acid

There total 4 articles about (R)-2-Hydroxy-4-(methylthio)butyric acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 108033-83-6
(R)-2-Hydroxy-4-methylsulfanyl-butyronitrile

: 39638-34-1
(R)-2-hydroxy-4-(methylthio)butanoic acid

Guidance literature:: With hydrogenchloride; 1a) r.t., 18 h, 1b) 60 deg C, 3 h, 1c) reflux, 2 h;
DOI:10.1055/s-1990-26945

Reference yield: 73.0%

: 63-68-3,26062-47-5,58576-49-1
L-methionine

: 39638-34-1
(R)-2-hydroxy-4-(methylthio)butanoic acid

Guidance literature:: With formate dehydrogenase; oxygen; ammonium formate; NADH; In aq. phosphate buffer; at 21 ℃; for 14h; under 750.075 Torr; pH=7; Concentration; stereoselective reaction; Enzymatic reaction;
DOI:10.1002/chem.201403195

Reference yield:

: 583-91-5
2-hydroxy 4-methylthiobutyric acid

: 39638-34-1
(R)-2-hydroxy-4-(methylthio)butanoic acid

Guidance literature:: With fatty acid photodecarboxylase from Chlorella variabilis NC₆₄A/G₄₆₂Y mutant; In aq. phosphate buffer; dimethyl sulfoxide; at 20 ℃; for 12h; pH=8.5; Reagent/catalyst; enantioselective reaction; Catalytic behavior; Irradiation; Resolution of racemate; Enzymatic reaction;
DOI:10.1002/anie.201903165