N-(4-methyloxyphenyl)-2-(5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl)sulfanylacetamide

Base Information

Chemical Name:N-(4-methyloxyphenyl)-2-(5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl)sulfanylacetamide
CAS No.:84327-83-3
Molecular Formula:C₁₇H₁₄ClN₃O₃S
Molecular Weight:375.835
Hs Code.:

Synonyms:N-(4-methyloxyphenyl)-2-(5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl)sulfanylacetamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-(4-methyloxyphenyl)-2-(5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl)sulfanylacetamide

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Technology Process of N-(4-methyloxyphenyl)-2-(5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl)sulfanylacetamide

There total 6 articles about N-(4-methyloxyphenyl)-2-(5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl)sulfanylacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 29182-87-4
2-bromo-N-(4-methoxyphenyl)acetamide

: 23766-28-1,203268-67-1
5-(4-chlorophenyl)-1,3,4-oxadiazole-2-thiol

: 84327-83-3
N-(4-methyloxyphenyl)-2-(5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl)sulfanylacetamide

Guidance literature:: With potassium carbonate; In acetone; at 20 ℃; for 6h;
DOI:10.1002/cjoc.201600501

Reference yield:

: 23766-28-1
5-(4-chlorophenyl)-2,3-dihydro-1,3,4-oxadiazole-2-thione

: 22303-36-2
N-(4-methoxyphenyl)-2-chloroacetamide

: 84327-83-3
N-(4-methyloxyphenyl)-2-(5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl)sulfanylacetamide

Guidance literature:: With potassium hydroxide; In ethanol; at 60 ℃; for 2h; Yield given;

Reference yield:

: 104-94-9
4-methoxy-aniline

: 84327-83-3
N-(4-methyloxyphenyl)-2-(5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl)sulfanylacetamide

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / dichloromethane

2: potassium carbonate / acetone / 6 h / 20 °C

With potassium carbonate; In dichloromethane; acetone;
DOI:10.1002/cjoc.201600501