Ethyl 2,5-dihydro-4-methoxy-5-oxo-3-phenyl-2-furanpropanoate

Base Information

Chemical Name:Ethyl 2,5-dihydro-4-methoxy-5-oxo-3-phenyl-2-furanpropanoate
CAS No.:105346-34-7
Molecular Formula:C16H18 O5
Molecular Weight:290.31
Hs Code.:
DSSTox Substance ID:DTXSID90909457
Nikkaji Number:J376.731K
Mol file:105346-34-7.mol

Synonyms:FR 62765;FR-62765

Suppliers and Price of Ethyl 2,5-dihydro-4-methoxy-5-oxo-3-phenyl-2-furanpropanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Ethyl 2,5-dihydro-4-methoxy-5-oxo-3-phenyl-2-furanpropanoate

Chemical Property:

Vapor Pressure:8.78E-09mmHg at 25°C
Boiling Point:463.8°Cat760mmHg
Flash Point:206.5°C
Density:1.2g/cm³
XLogP3:2.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:7
Exact Mass:290.11542367
Heavy Atom Count:21
Complexity:420

Purity/Quality:: >98 % ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)CCC1C(=C(C(=O)O1)OC)C2=CC=CC=C2

Technology Process of Ethyl 2,5-dihydro-4-methoxy-5-oxo-3-phenyl-2-furanpropanoate

There total 3 articles about Ethyl 2,5-dihydro-4-methoxy-5-oxo-3-phenyl-2-furanpropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 105346-32-5
ethyl 3-(4-hydroxy-5-oxo-3-phenyl-2,5-dihydro-2-furyl)propionate

: 105346-34-7
3-(4-methoxy-5-oxo-3-phenyl-2,5-dihydrofuran-2-yl)propanoic acid ethyl ester

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; for 4h; Ambient temperature;
DOI:10.1248/cpb.36.1404

Reference yield:

: 156-06-9
2-oxo-3-(phenyl)propionic acid

: 105346-34-7
3-(4-methoxy-5-oxo-3-phenyl-2,5-dihydrofuran-2-yl)propanoic acid ethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 87 percent / DBU / dimethylformamide / 2.5 h / 0 °C

2: 72 percent / DBU / dimethylformamide / 2.5 h

3: 77 percent / K₂CO₃ / dimethylformamide / 4 h / Ambient temperature

With potassium carbonate; 1,8-diazabicyclo[5.4.0]undec-7-ene; In N,N-dimethyl-formamide;
DOI:10.1248/cpb.36.1404

Reference yield:

: 6362-58-9
methyl phenylpyruvate

: 105346-34-7
3-(4-methoxy-5-oxo-3-phenyl-2,5-dihydrofuran-2-yl)propanoic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 72 percent / DBU / dimethylformamide / 2.5 h

2: 77 percent / K₂CO₃ / dimethylformamide / 4 h / Ambient temperature

With potassium carbonate; 1,8-diazabicyclo[5.4.0]undec-7-ene; In N,N-dimethyl-formamide;
DOI:10.1248/cpb.36.1404