(4S,5S)-cis-4-(ethoxycarbonyl)-5-(4-chlorophenyl)-1-N-tosyl-2-imidazoline

Base Information

Chemical Name:(4S,5S)-cis-4-(ethoxycarbonyl)-5-(4-chlorophenyl)-1-N-tosyl-2-imidazoline
CAS No.:228702-93-0
Molecular Formula:C₁₉H₁₉ClN₂O₄S
Molecular Weight:406.89
Hs Code.:

Synonyms:(4S,5S)-cis-4-(ethoxycarbonyl)-5-(4-chlorophenyl)-1-N-tosyl-2-imidazoline

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (4S,5S)-cis-4-(ethoxycarbonyl)-5-(4-chlorophenyl)-1-N-tosyl-2-imidazoline

Chemical Property:

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Technology Process of (4S,5S)-cis-4-(ethoxycarbonyl)-5-(4-chlorophenyl)-1-N-tosyl-2-imidazoline

There total 2 articles about (4S,5S)-cis-4-(ethoxycarbonyl)-5-(4-chlorophenyl)-1-N-tosyl-2-imidazoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

: 2999-46-4
Ethyl isocyanoacetate

: 3157-65-1
N-(p-chlorobenzylidene)-p-toluenesulfonamide

: 221000-81-3
(4R,5R)-cis-4-(ethoxycarbonyl)-5-(4-chlorophenyl)-1-N-tosyl-2-imidazoline

: 228702-93-0
(4S,5S)-cis-4-(ethoxycarbonyl)-5-(4-chlorophenyl)-1-N-tosyl-2-imidazoline

: trans-4-(ethoxycarbonyl)-5-(4-chlorophenyl)-1-N-tosyl-2-imidazoline

Guidance literature:: dimethylsulfide gold(I) chloride; (Ph₂PC₅H₄)Fe(Ph₂PC₅H₃CHMeNMeCH₂CH₂N(CH₂)5); In dichloromethane; at 25 ℃; for 24h;
DOI:10.1021/jo980949s

Reference yield: 31.0%

: 2999-46-4
Ethyl isocyanoacetate

: 3157-65-1
N-(p-chlorobenzylidene)-p-toluenesulfonamide

: 228702-93-0
(4S,5S)-cis-4-(ethoxycarbonyl)-5-(4-chlorophenyl)-1-N-tosyl-2-imidazoline

Guidance literature:: With dimethylsulfide gold(I) chloride; (S,R)-chiral ferrocenylphosphine; In dichloromethane; at 25 ℃; for 20h;
DOI:10.1016/S0957-4166(99)00052-X