(S)-N₁-(2,6-diisopropylphenyl)-N₂-(1-hydroxy-3-phenylpropan-2-yl)oxalamide

Base Information

Chemical Name:(S)-N₁-(2,6-diisopropylphenyl)-N₂-(1-hydroxy-3-phenylpropan-2-yl)oxalamide
CAS No.:1358742-52-5
Molecular Formula:C₂₃H₃₀N₂O₃
Molecular Weight:382.503
Hs Code.:

(S)-N<sub>1</sub>-(2,6-diisopropylphenyl)-N<sub>2</sub>-(1-hydroxy-3-phenylpropan-2-yl)oxalamide

Synonyms:(S)-N₁-(2,6-diisopropylphenyl)-N₂-(1-hydroxy-3-phenylpropan-2-yl)oxalamide

Suppliers and Price of (S)-N₁-(2,6-diisopropylphenyl)-N₂-(1-hydroxy-3-phenylpropan-2-yl)oxalamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (S)-N₁-(2,6-diisopropylphenyl)-N₂-(1-hydroxy-3-phenylpropan-2-yl)oxalamide

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Technology Process of (S)-N₁-(2,6-diisopropylphenyl)-N₂-(1-hydroxy-3-phenylpropan-2-yl)oxalamide

There total 2 articles about (S)-N₁-(2,6-diisopropylphenyl)-N₂-(1-hydroxy-3-phenylpropan-2-yl)oxalamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 3182-95-4
L-Phenylalaninol

: 609798-47-2
ethyl 2-((2,6-diisopropylphenyl)amino)-2-oxoacetate

: 1358742-52-5
(S)-N₁-(2,6-diisopropylphenyl)-N₂-(1-hydroxy-3-phenylpropan-2-yl)oxalamide

Guidance literature:: In dichloromethane; Inert atmosphere; Reflux;
DOI:10.1016/j.tetasy.2011.11.015

Reference yield:

: 63-91-2,25191-15-5,658-69-5,67675-33-6
L-phenylalanine

: 1358742-52-5
(S)-N₁-(2,6-diisopropylphenyl)-N₂-(1-hydroxy-3-phenylpropan-2-yl)oxalamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: lithium aluminium tetrahydride / tetrahydrofuran / Inert atmosphere

1.2: Inert atmosphere

2.1: dichloromethane / Inert atmosphere; Reflux

With lithium aluminium tetrahydride; In tetrahydrofuran; dichloromethane;
DOI:10.1016/j.tetasy.2011.11.015