3-{2-[5-(toluene-4-sulfonyl)-5H-[1,3]dithiolo[4,5-c]pyrrol-2-ylidene]-[1,3]dithiol-4-ylsulfanyl}-propionitrile

Base Information

• Chemical Name: 3-{2-[5-(toluene-4-sulfonyl)-5H-[1,3]dithiolo[4,5-c]pyrrol-2-ylidene]-[1,3]dithiol-4-ylsulfanyl}-propionitrile
• CAS No.: 861389-60-8
• Molecular Formula: C₁₈H₁₄N₂O₂S₆
• Molecular Weight: 482.717
• Mol file: 861389-60-8.mol

Synonyms:3-{2-[5-(toluene-4-sulfonyl)-5H-[1,3]dithiolo[4,5-c]pyrrol-2-ylidene]-[1,3]dithiol-4-ylsulfanyl}-propionitrile

Chemical Property of 3-{2-[5-(toluene-4-sulfonyl)-5H-[1,3]dithiolo[4,5-c]pyrrol-2-ylidene]-[1,3]dithiol-4-ylsulfanyl}-propionitrile

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-{2-[5-(toluene-4-sulfonyl)-5H-[1,3]dithiolo[4,5-c]pyrrol-2-ylidene]-[1,3]dithiol-4-ylsulfanyl}-propionitrile

There total 1 articles about 3-{2-[5-(toluene-4-sulfonyl)-5H-[1,3]dithiolo[4,5-c]pyrrol-2-ylidene]-[1,3]dithiol-4-ylsulfanyl}-propionitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

5-tosyl-[1,3]dithiolo[4,5-c]pyrrol-2-one (250687-28-6) + 4-(2-cyanoethyl)thio-1,3-dithiolane-2-thione (349580-76-3) → 3-{2-[5-(toluene-4-sulfonyl)-5H-[1,3]dithiolo[4,5-c]pyrrol-2-ylidene]-[1,3]dithiol-4-ylsulfanyl}-propionitrile (861389-60-8)

Guidance literature:

With triethyl phosphite; at 135 ℃; for 2.5h;

DOI:10.1002/ejoc.200400530

Reference yield: 98.0%

methyl iodide (74-88-4) + 3-{2-[5-(toluene-4-sulfonyl)-5H-[1,3]dithiolo[4,5-c]pyrrol-2-ylidene]-[1,3]dithiol-4-ylsulfanyl}-propionitrile (861389-60-8) → 2-(4-methylsulfanyl-[1,3]dithiol-2-ylidene)-5-(toluene-4-sulfonyl)-5H-[1,3]dithiolo[4,5-c]pyrrole (848153-15-1)

Guidance literature:

3-{2-[5-(toluene-4-sulfonyl)-5H-[1,3]dithiolo[4,5-c]pyrrol-2-ylidene]-[1,3]dithiol-4-ylsulfanyl}-propionitrile; With cesium hydroxide; In tetrahydrofuran; methanol; at 20 ℃; for 1.08333h;

methyl iodide; In tetrahydrofuran; methanol; at 20 ℃; for 2h;

DOI:10.1002/ejoc.200400530

Reference yield: 70.0%

3-{2-[5-(toluene-4-sulfonyl)-5H-[1,3]dithiolo[4,5-c]pyrrol-2-ylidene]-[1,3]dithiol-4-ylsulfanyl}-propionitrile (861389-60-8) + 1-[2-(2-{4-[bis-(4-tert-butyl-phenyl)-(4-ethyl-phenyl)-methyl]-phenoxy}-ethoxy)-ethoxy]-5-[2-(2-iodo-ethoxy)-ethoxy]-naphthalene (603131-42-6) → 2-{4-[2-(2-{5-[2-(2-{4-[bis-(4-tert-butyl-phenyl)-(4-ethyl-phenyl)-methyl]-phenoxy}-ethoxy)-ethoxy]-naphthalen-1-yloxy}-ethoxy)-ethylsulfanyl]-[1,3]dithiol-2-ylidene}-5-(toluene-4-sulfonyl)-5H-[1,3]dithiolo[4,5-c]pyrrole (848153-10-6)

Guidance literature:

3-{2-[5-(toluene-4-sulfonyl)-5H-[1,3]dithiolo[4,5-c]pyrrol-2-ylidene]-[1,3]dithiol-4-ylsulfanyl}-propionitrile; With cesium hydroxide; In tetrahydrofuran; methanol; at 20 ℃; for 1h;

1-[2-(2-{4-[bis-(4-tert-butyl-phenyl)-(4-ethyl-phenyl)-methyl]-phenoxy}-ethoxy)-ethoxy]-5-[2-(2-iodo-ethoxy)-ethoxy]-naphthalene; In tetrahydrofuran; methanol; at 20 ℃; for 24h;

DOI:10.1002/ejoc.200400530

upstream raw materials:

5-tosyl-[1,3]dithiolo[4,5-c]pyrrol-2-one

4-(2-cyanoethyl)thio-1,3-dithiolane-2-thione

Downstream raw materials:

2-(4-methylsulfanyl-[1,3]dithiol-2-ylidene)-5-(toluene-4-sulfonyl)-5H-[1,3]dithiolo[4,5-c]pyrrole

2-{4-[2-(2-{5-[2-(2-{4-[bis-(4-tert-butyl-phenyl)-(4-ethyl-phenyl)-methyl]-phenoxy}-ethoxy)-ethoxy]-naphthalen-1-yloxy}-ethoxy)-ethylsulfanyl]-[1,3]dithiol-2-ylidene}-5-(toluene-4-sulfonyl)-5H-[1,3]dithiolo[4,5-c]pyrrole

2-{4-(2-{2-[2-(tetrahydropyranyl-2-oxy)ethoxy]ethoxy}ethylthio)-1,3-dithiol-2-ylidene}-5-tosyl-(1,3)-dithiolo[4,5-c]pyrrole