(S)-2-(3-benzyloxycarbonylamino-2-oxo-2H-pyridin-1-yl)-4-methylpentanoic acid methyl ester

Base Information

Chemical Name:(S)-2-(3-benzyloxycarbonylamino-2-oxo-2H-pyridin-1-yl)-4-methylpentanoic acid methyl ester
CAS No.:1314531-65-1
Molecular Formula:C₂₀H₂₄N₂O₅
Molecular Weight:372.421
Hs Code.:

Synonyms:(S)-2-(3-benzyloxycarbonylamino-2-oxo-2H-pyridin-1-yl)-4-methylpentanoic acid methyl ester

Suppliers and Price of (S)-2-(3-benzyloxycarbonylamino-2-oxo-2H-pyridin-1-yl)-4-methylpentanoic acid methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S)-2-(3-benzyloxycarbonylamino-2-oxo-2H-pyridin-1-yl)-4-methylpentanoic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-2-(3-benzyloxycarbonylamino-2-oxo-2H-pyridin-1-yl)-4-methylpentanoic acid methyl ester

There total 3 articles about (S)-2-(3-benzyloxycarbonylamino-2-oxo-2H-pyridin-1-yl)-4-methylpentanoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

: 146746-21-6
(S)-2-methanesulfonyloxy-4-methylpentanoic acid methyl ester

: 147269-67-8
3-(benzyloxycarbonylamino)pyrid-2-one

: 1314531-65-1
(S)-2-(3-benzyloxycarbonylamino-2-oxo-2H-pyridin-1-yl)-4-methylpentanoic acid methyl ester

Guidance literature:: 3-(benzyloxycarbonylamino)pyrid-2-one; With sodium hydride; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 1h; Inert atmosphere;

(S)-2-methanesulfonyloxy-4-methylpentanoic acid methyl ester; In N,N-dimethyl-formamide; at 20 ℃; for 12h; Inert atmosphere;
DOI:10.1002/cmdc.201100093

Reference yield:

: 17392-84-6
methyl (2S)-2-hydroxy-4-methylpentanoate

: 1314531-65-1
(S)-2-(3-benzyloxycarbonylamino-2-oxo-2H-pyridin-1-yl)-4-methylpentanoic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1.1: triethylamine / dichloromethane / 2 h / 20 °C / Inert atmosphere

2.1: sodium hydride / N,N-dimethyl-formamide / 1 h / 0 - 20 °C / Inert atmosphere

2.2: 12 h / 20 °C / Inert atmosphere

With sodium hydride; triethylamine; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1002/cmdc.201100093

Reference yield:

: 33630-99-8
3-amino-2-pyridone

: 1314531-65-1
(S)-2-(3-benzyloxycarbonylamino-2-oxo-2H-pyridin-1-yl)-4-methylpentanoic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydrogencarbonate / 1,4-dioxane; water / 12 h / 0 - 20 °C

2.1: sodium hydride / N,N-dimethyl-formamide / 1 h / 0 - 20 °C / Inert atmosphere

2.2: 12 h / 20 °C / Inert atmosphere

With sodium hydride; sodium hydrogencarbonate; In 1,4-dioxane; water; N,N-dimethyl-formamide;
DOI:10.1002/cmdc.201100093