1R(1α,2β,3α,4α,5β)-3-acetoxy-4-benzyloxy-2-(O-benzylhydroxylamino)-1',5-(isopropylidenedioxy)-1-methyl-1-cyclopentanol

Base Information

• Chemical Name: 1R(1α,2β,3α,4α,5β)-3-acetoxy-4-benzyloxy-2-(O-benzylhydroxylamino)-1',5-(isopropylidenedioxy)-1-methyl-1-cyclopentanol
• CAS No.: 252209-26-0
• Molecular Formula: C₂₅H₃₁NO₇
• Molecular Weight: 457.524
• Mol file: 252209-26-0.mol

Synonyms:1R(1α,2β,3α,4α,5β)-3-acetoxy-4-benzyloxy-2-(O-benzylhydroxylamino)-1',5-(isopropylidenedioxy)-1-methyl-1-cyclopentanol

Chemical Property of 1R(1α,2β,3α,4α,5β)-3-acetoxy-4-benzyloxy-2-(O-benzylhydroxylamino)-1',5-(isopropylidenedioxy)-1-methyl-1-cyclopentanol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1R(1α,2β,3α,4α,5β)-3-acetoxy-4-benzyloxy-2-(O-benzylhydroxylamino)-1',5-(isopropylidenedioxy)-1-methyl-1-cyclopentanol

There total 1 articles about 1R(1α,2β,3α,4α,5β)-3-acetoxy-4-benzyloxy-2-(O-benzylhydroxylamino)-1',5-(isopropylidenedioxy)-1-methyl-1-cyclopentanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

2-O-acetyl-3-O-benzyl-1-(O-benzyloximino)-4,6-O-isopropylidene-D-lyxo-hexos-5-ulose → 1R(1α,2β,3α,4α,5β)-3-acetoxy-4-benzyloxy-2-(O-benzylhydroxylamino)-1',5-(isopropylidenedioxy)-1-methyl-1-cyclopentanol (252209-26-0)

Guidance literature:

With samarium diiodide; In tetrahydrofuran; tert-butyl alcohol; at -30 ℃; for 1h;

DOI:10.1021/ol990904t

Reference yield: 99.0%

1R(1α,2β,3α,4α,5β)-3-acetoxy-4-benzyloxy-2-(O-benzylhydroxylamino)-1',5-(isopropylidenedioxy)-1-methyl-1-cyclopentanol (252209-26-0) → 1R(1α,2β,3α,4α,5β)-4-benzyloxy-2-(O-benzylhydroxylamino)-1',5-(isopropylidenedioxy)-1-methyl-1,3-cyclopentanodiol

Guidance literature:

With ammonia; In tetrahydrofuran; methanol; at 20 ℃; for 2h;

DOI:10.1021/ol990904t

Reference yield:

1R(1α,2β,3α,4α,5β)-3-acetoxy-4-benzyloxy-2-(O-benzylhydroxylamino)-1',5-(isopropylidenedioxy)-1-methyl-1-cyclopentanol (252209-26-0) → C18H25NO6

Guidance literature:

With water; In tetrahydrofuran; tert-butyl alcohol; at 20 ℃; for 0.5h;

DOI:10.1021/ol990904t

Downstream raw materials:

1R(1α,2β,3α,4α,5β)-2-acetamido-3-acetoxy-4-benzyloxy-1',5-(isopropylidenedioxy)-1-methyl-1-cyclopentanol

1R(1α,2β,3α,4α,5β)-2-amino-4-benzyloxy-1',5-(isopropylidenedioxy)-1-methyl-1,3-cyclopentanediol

1R(1α,2β,3α,4α,5β)-2-acetamido-4-benzyloxy-1',5-(isopropylidenedioxy)-1-methyl-1,3-cyclopentanediol

C₁₈H₂₃NO₅