2-<3-(5-Chlor-2-methyl)thienyl>-α-hydroxy-3-phenyl-N-(tetrahydropyranyl-2-oxy)propanamid

Base Information

Chemical Name:2-<3-(5-Chlor-2-methyl)thienyl>-α-hydroxy-3-phenyl-N-(tetrahydropyranyl-2-oxy)propanamid
CAS No.:154421-77-9
Molecular Formula:C₁₉H₂₂ClNO₄S
Molecular Weight:395.907
Hs Code.:

Synonyms:2-<3-(5-Chlor-2-methyl)thienyl>-α-hydroxy-3-phenyl-N-(tetrahydropyranyl-2-oxy)propanamid

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-<3-(5-Chlor-2-methyl)thienyl>-α-hydroxy-3-phenyl-N-(tetrahydropyranyl-2-oxy)propanamid

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Technology Process of 2-<3-(5-Chlor-2-methyl)thienyl>-α-hydroxy-3-phenyl-N-(tetrahydropyranyl-2-oxy)propanamid

There total 3 articles about 2-<3-(5-Chlor-2-methyl)thienyl>-α-hydroxy-3-phenyl-N-(tetrahydropyranyl-2-oxy)propanamid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 17249-82-0
2-chloro-5-methylthiophene

: 154421-77-9
2-<3-(5-Chlor-2-methyl)thienyl>-α-hydroxy-3-phenyl-N-(tetrahydropyranyl-2-oxy)propanamid

Guidance literature:: Multi-step reaction with 3 steps

1: 61 percent / AlCl₃

2: 2) NaOH

3: 1) 1,1'-carbonyldiimidazole / 1) CH₂Cl₂, 0.5 h, 2) CH₂Cl₂, RT, 24 h

With sodium hydroxide; aluminium trichloride; 1,1'-carbonyldiimidazole;

Reference yield:

: 154421-63-3
<3-(5-Chlor-2-methyl)thienyl>glycolsaeureethylester

: 154421-77-9
2-<3-(5-Chlor-2-methyl)thienyl>-α-hydroxy-3-phenyl-N-(tetrahydropyranyl-2-oxy)propanamid

Guidance literature:: Multi-step reaction with 2 steps

1: 2) NaOH

2: 1) 1,1'-carbonyldiimidazole / 1) CH₂Cl₂, 0.5 h, 2) CH₂Cl₂, RT, 24 h

With sodium hydroxide; 1,1'-carbonyldiimidazole;