(S)-tert-butyl 4-(2-(4-(4-chlorophenyl)-4-hydroxy-3,3-dimethylpiperidin-1-yl)-2-oxoethyl)tetrahydro-2H-pyran-4-ylcarbamate

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Chemical Name:(S)-tert-butyl 4-(2-(4-(4-chlorophenyl)-4-hydroxy-3,3-dimethylpiperidin-1-yl)-2-oxoethyl)tetrahydro-2H-pyran-4-ylcarbamate
CAS No.:1108154-48-8
Molecular Formula:C₂₅H₃₇ClN₂O₅
Molecular Weight:481.032
Hs Code.:

Synonyms:(S)-tert-butyl 4-(2-(4-(4-chlorophenyl)-4-hydroxy-3,3-dimethylpiperidin-1-yl)-2-oxoethyl)tetrahydro-2H-pyran-4-ylcarbamate

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Chemical Property of (S)-tert-butyl 4-(2-(4-(4-chlorophenyl)-4-hydroxy-3,3-dimethylpiperidin-1-yl)-2-oxoethyl)tetrahydro-2H-pyran-4-ylcarbamate

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Technology Process of (S)-tert-butyl 4-(2-(4-(4-chlorophenyl)-4-hydroxy-3,3-dimethylpiperidin-1-yl)-2-oxoethyl)tetrahydro-2H-pyran-4-ylcarbamate

There total 1 articles about (S)-tert-butyl 4-(2-(4-(4-chlorophenyl)-4-hydroxy-3,3-dimethylpiperidin-1-yl)-2-oxoethyl)tetrahydro-2H-pyran-4-ylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 690660-22-1
(S)-4-(4-chlorophenyl)-3,3-dimethylpiperidin-4-ol

: 946682-30-0
2-(4-(tert-butoxycarbonylamino)tetrahydro-2H-pyran-4-yl)acetic acid

: 1108154-48-8
(S)-tert-butyl 4-(2-(4-(4-chlorophenyl)-4-hydroxy-3,3-dimethylpiperidin-1-yl)-2-oxoethyl)tetrahydro-2H-pyran-4-ylcarbamate

Guidance literature:: With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃; for 20h;

Reference yield:

: 1108154-48-8
(S)-tert-butyl 4-(2-(4-(4-chlorophenyl)-4-hydroxy-3,3-dimethylpiperidin-1-yl)-2-oxoethyl)tetrahydro-2H-pyran-4-ylcarbamate

: 1108154-49-9
(S)-2-(4-aminotetrahydro-2H-pyran-4-yl)-1-(4-(4-chlorophenyl)-4-hydroxy-3,3-dimethylpiperidin-1-yl)ethanone

Guidance literature:: (S)-tert-butyl 4-(2-(4-(4-chlorophenyl)-4-hydroxy-3,3-dimethylpiperidin-1-yl)-2-oxoethyl)tetrahydro-2H-pyran-4-ylcarbamate; With hydrogenchloride; In 1,4-dioxane; at 20 ℃; for 24h;

With sodium hydroxide; In 1,4-dioxane; ethyl acetate;