{4-[(tert-Butoxycarbonyl)amino]tetrahydro-2H-pyran-4-yl}acetic acid

Base Information

Chemical Name:{4-[(tert-Butoxycarbonyl)amino]tetrahydro-2H-pyran-4-yl}acetic acid
CAS No.:946682-30-0
Molecular Formula:C12H21NO5
Molecular Weight:259.29884
Hs Code.:2932990090
European Community (EC) Number:968-254-3
Mol file:946682-30-0.mol

Synonyms:946682-30-0;(4-Boc-amino-tetrahydropyran-4-yl)acetic acid;{4-[(tert-Butoxycarbonyl)amino]tetrahydro-2H-pyran-4-yl}acetic acid;(4-BOC-AMINO-TETRAHYDROPYRAN-4-YL)-ACETIC ACID;2-(4-{[(tert-butoxy)carbonyl]amino}oxan-4-yl)acetic acid;2-(4-((TERT-BUTOXYCARBONYL)AMINO)TETRAHYDRO-2H-PYRAN-4-YL)ACETIC ACID;{4-[(tert-butoxycarbonyl)amino]oxan-4-yl}acetic acid;2-[4-[(2-methylpropan-2-yl)oxycarbonylamino]oxan-4-yl]acetic acid;SCHEMBL3019001;NFOXLDGTCZNVBA-UHFFFAOYSA-N;MFCD09264196;AKOS025393494;PS-7374;DA-21753;N-Boc-2-(4-Aminooxan-4-yl)acetic acid;CS-0434914;(4-Boc-amino-tetrahydropyran-4-yl)aceticacid;EN300-306771;[4-Amino(tetrahydro-2H-pyran-4-yl)]acetic acid, N-BOC protected;2-(4-(tert-Butoxycarbonylamino)tetrahydro-2H-pyran-4-yl)acetic acid

Suppliers and Price of {4-[(tert-Butoxycarbonyl)amino]tetrahydro-2H-pyran-4-yl}acetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
{4-[(tert-Butoxycarbonyl)amino]tetrahydro-2H-pyran-4-yl}acetic acid
100 mg
$ 72.00

SynQuest Laboratories
{4-[(tert-Butoxycarbonyl)amino]tetrahydro-2H-pyran-4-yl}acetic acid
250 mg
$ 146.00

SynQuest Laboratories
{4-[(tert-Butoxycarbonyl)amino]tetrahydro-2H-pyran-4-yl}acetic acid
1 g
$ 288.00

Iris Biotech GmbH
(Boc-NH-THP)aceticacid
25 g
$ 4077.00

Iris Biotech GmbH
(Boc-NH-THP)aceticacid
1 g
$ 256.50

Iris Biotech GmbH
(Boc-NH-THP)aceticacid
5 g
$ 1026.00

Crysdot
(4-Boc-amino-tetrahydropyran-4-yl)aceticacid 95+%
5g
$ 952.00

Chemenu
(4-Boc-amino-tetrahydropyran-4-yl)aceticacid 95%
5g
$ 898.00

Biosynth Carbosynth
(4-Boc-amino-tetrahydropyran-4-yl)acetic acid
500 mg
$ 300.00

Biosynth Carbosynth
(4-Boc-amino-tetrahydropyran-4-yl)acetic acid
250 mg
$ 250.00

Total 5 raw suppliers

Chemical Property of {4-[(tert-Butoxycarbonyl)amino]tetrahydro-2H-pyran-4-yl}acetic acid

Chemical Property:

PSA：88.35000
LogP:1.73940
XLogP3:1.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:259.14197277
Heavy Atom Count:18
Complexity:315

Purity/Quality:

97% ^*data from raw suppliers

{4-[(tert-Butoxycarbonyl)amino]tetrahydro-2H-pyran-4-yl}acetic acid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC1(CCOCC1)CC(=O)O

Technology Process of {4-[(tert-Butoxycarbonyl)amino]tetrahydro-2H-pyran-4-yl}acetic acid

There total 1 articles about {4-[(tert-Butoxycarbonyl)amino]tetrahydro-2H-pyran-4-yl}acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1108154-46-6
methyl 2-(4-(tert-butoxycarbonylamino)tetrahydro-2H-pyran-4-yl)acetate

: 946682-30-0
2-(4-(tert-butoxycarbonylamino)tetrahydro-2H-pyran-4-yl)acetic acid

Guidance literature:: methyl 2-(4-(tert-butoxycarbonylamino)tetrahydro-2H-pyran-4-yl)acetate; With water; potassium hydroxide; In ethanol; water; at 20 - 60 ℃;

With hydrogenchloride; In ethanol; water; ethyl acetate;

Reference yield: 63.0%

: 946682-30-0
2-(4-(tert-butoxycarbonylamino)tetrahydro-2H-pyran-4-yl)acetic acid

: 100-39-0
benzyl bromide

: 1413936-79-4
benzyl 2-(4-(tert-butoxycarbonylamino) tetrahydro-2H-pyran-4-yl)acetate

Guidance literature:: With potassium carbonate; In tetrahydrofuran; for 3h; Reflux;
DOI:10.3762/bjoc.8.142

Reference yield:

: 690660-22-1
(S)-4-(4-chlorophenyl)-3,3-dimethylpiperidin-4-ol

: 946682-30-0
2-(4-(tert-butoxycarbonylamino)tetrahydro-2H-pyran-4-yl)acetic acid

: 1108154-48-8
(S)-tert-butyl 4-(2-(4-(4-chlorophenyl)-4-hydroxy-3,3-dimethylpiperidin-1-yl)-2-oxoethyl)tetrahydro-2H-pyran-4-ylcarbamate

Guidance literature:: With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃; for 20h;