Chemical Property of Glibornuride
Chemical Property:
- Melting Point:192-195° (ethanol-water); also reported as 195-198°
- Refractive Index:1.6930 (estimate)
- Boiling Point:°Cat760mmHg
- PKA:5.20±0.10(Predicted)
- Flash Point:°C
- PSA:107.37000
- Density:1.3g/cm3
- LogP:3.84460
- XLogP3:3.2
- Hydrogen Bond Donor Count:3
- Hydrogen Bond Acceptor Count:4
- Rotatable Bond Count:3
- Exact Mass:366.16132849
- Heavy Atom Count:25
- Complexity:634
- Purity/Quality:
-
99%, *data from raw suppliers
Glibornuride *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- MSDS Files:
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SDS file from LookChem
Useful:
- Canonical SMILES:CC1=CC=C(C=C1)S(=O)(=O)NC(=O)NC2C3CCC(C2O)(C3(C)C)C
- Isomeric SMILES:CC1=CC=C(C=C1)S(=O)(=O)NC(=O)N[C@H]2[C@H]3CC[C@@]([C@H]2O)(C3(C)C)C
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Uses
Glibornuride has been shown to antagonize the relaxant response to the K+ channel opener cromakalim and produce airway smooth muscle relaxation. Glibornuride is associated with lactic acidosis and hypoglycemia in patients with type 2 diabetes melitus.
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Therapeutic Function
Oral hypoglycemic