5-[5-(2-pyridyl)-4-azaphthalimido]isophthaloyl dichloride

Base Information

• Chemical Name: 5-[5-(2-pyridyl)-4-azaphthalimido]isophthaloyl dichloride
• CAS No.: 1416579-73-1
• Molecular Formula: C₂₀H₉Cl₂N₃O₄
• Molecular Weight: 426.215
• Mol file: 1416579-73-1.mol

Synonyms:5-[5-(2-pyridyl)-4-azaphthalimido]isophthaloyl dichloride

Chemical Property of 5-[5-(2-pyridyl)-4-azaphthalimido]isophthaloyl dichloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-[5-(2-pyridyl)-4-azaphthalimido]isophthaloyl dichloride

There total 5 articles about 5-[5-(2-pyridyl)-4-azaphthalimido]isophthaloyl dichloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

5-[5-(2-pyridyl)-4-azaphthalimido]isophthalic acid (1416579-72-0) → 5-[5-(2-pyridyl)-4-azaphthalimido]isophthaloyl dichloride (1416579-73-1)

Guidance literature:

With thionyl chloride; In neat (no solvent); for 5h; Reflux;

DOI:10.1007/s11172-012-0139-x

Reference yield:

2-(pyridin-2-yl)-quinoline-4-carboxylic acid (57882-27-6) → 5-[5-(2-pyridyl)-4-azaphthalimido]isophthaloyl dichloride (1416579-73-1)

Guidance literature:

Multi-step reaction with 4 steps

1: potassium permanganate

2: acetic anhydride; acetic acid

4: thionyl chloride

With potassium permanganate; thionyl chloride; acetic anhydride; acetic acid;

DOI:10.1134/S1070427212110134

Reference yield:

6-(2-pyridyl)pyridine-2,3,4-tricarboxylic acid (1416579-70-8) → 5-[5-(2-pyridyl)-4-azaphthalimido]isophthaloyl dichloride (1416579-73-1)

Guidance literature:

Multi-step reaction with 3 steps

1: acetic anhydride; acetic acid

3: thionyl chloride

With thionyl chloride; acetic anhydride; acetic acid;

DOI:10.1134/S1070427212110134

upstream raw materials:

2-acetylpyridine

2-(pyridin-2-yl)-quinoline-4-carboxylic acid

6-(2-pyridyl)pyridine-2,3,4-tricarboxylic acid

6-(2-pyridyl)pyridine-3,4-dicarboxylic acid anhydride