methyl 2-L--3-phthalimidopropanoate

Base Information

• Chemical Name: methyl 2-L--3-phthalimidopropanoate
• CAS No.: 175672-86-3
• Molecular Formula: C₂₀H₁₈N₂O₆
• Molecular Weight: 382.373
• Mol file: 175672-86-3.mol

Synonyms:methyl 2-L--3-phthalimidopropanoate

Chemical Property of methyl 2-L--3-phthalimidopropanoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 2-L--3-phthalimidopropanoate

There total 5 articles about methyl 2-L--3-phthalimidopropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

methanol (67-56-1) + (2S)-N2-carbobenzoxy-N3-phthaloyl-2,3-diaminopropionic acid (147635-15-2) → methyl 2-L--3-phthalimidopropanoate (175672-86-3)

Guidance literature:

With thionyl chloride; for 18h; Ambient temperature;

DOI:10.1021/jm9606453

Reference yield: 73.0%

phthalimide (136918-14-4,85-41-6) + N-benzyloxycarbonyl-L-serine methyl ester (1676-81-9) → methyl 2-(benzyloxycarbonylamino)acrylate (21149-17-7) + methyl 2-L--3-phthalimidopropanoate (175672-86-3)

Guidance literature:

With triphenylphosphine; diethylazodicarboxylate; In benzene; for 15h; Ambient temperature;

DOI:10.1021/jo951958t

Reference yield: 13.0%

N-benzyloxycarbonyl-L-serine methyl ester (1676-81-9) → methyl 2-(benzyloxycarbonylamino)acrylate (21149-17-7) + methyl 2-L--3-phthalimidopropanoate (175672-86-3)

Guidance literature:

With phthalimide; triphenylphosphine; diethylazodicarboxylate; In benzene; for 15h; Ambient temperature; other reagent: 4-nitrobenzoic acid;

DOI:10.1021/jo951958t

upstream raw materials:

phthalimide

N-benzyloxycarbonyl-L-serine methyl ester

methanol

(2S)-N²-carbobenzoxy-N³-phthaloyl-2,3-diaminopropionic acid