5-(4-fluoro-3-methoxy-phenyl)-1-(4-methanesulfonyl-phenyl)-1H-imidazole

Base Information

Chemical Name:5-(4-fluoro-3-methoxy-phenyl)-1-(4-methanesulfonyl-phenyl)-1H-imidazole
CAS No.:1027417-58-8
Molecular Formula:C₁₇H₁₅FN₂O₃S
Molecular Weight:346.382
Hs Code.:

5-(4-fluoro-3-methoxy-phenyl)-1-(4-methanesulfonyl-phenyl)-1<i>H</i>-imidazole

Synonyms:5-(4-fluoro-3-methoxy-phenyl)-1-(4-methanesulfonyl-phenyl)-1H-imidazole

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Chemical Property of 5-(4-fluoro-3-methoxy-phenyl)-1-(4-methanesulfonyl-phenyl)-1H-imidazole

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Technology Process of 5-(4-fluoro-3-methoxy-phenyl)-1-(4-methanesulfonyl-phenyl)-1H-imidazole

There total 4 articles about 5-(4-fluoro-3-methoxy-phenyl)-1-(4-methanesulfonyl-phenyl)-1H-imidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 5470-49-5
4-methanesulfonylphenylamine

: 1027417-58-8
5-(4-fluoro-3-methoxy-phenyl)-1-(4-methanesulfonyl-phenyl)-1H-imidazole

Guidance literature:: Multi-step reaction with 2 steps

1: toluene / Heating

2: K₂CO₃ / methanol; 1,2-dimethoxy-ethane / Heating

With potassium carbonate; In methanol; 1,2-dimethoxyethane; toluene;
DOI:10.1021/jm030765s

Reference yield:

: 128495-46-5
4-fluoro-3-methoxybenzaldehyde

: 1027417-58-8
5-(4-fluoro-3-methoxy-phenyl)-1-(4-methanesulfonyl-phenyl)-1H-imidazole

Guidance literature:: Multi-step reaction with 2 steps

1: toluene / Heating

2: K₂CO₃ / methanol; 1,2-dimethoxy-ethane / Heating

With potassium carbonate; In methanol; 1,2-dimethoxyethane; toluene;
DOI:10.1021/jm030765s

Reference yield:

: 104-96-1
4-methylsulfanylaniline

: 1027417-58-8
5-(4-fluoro-3-methoxy-phenyl)-1-(4-methanesulfonyl-phenyl)-1H-imidazole

Guidance literature:: Multi-step reaction with 3 steps

1: 75 percent / Na₂WO₄; acetic acid; aq. H₂O₂ / 1.5 h / 65 °C

2: toluene / Heating

3: K₂CO₃ / methanol; 1,2-dimethoxy-ethane / Heating

With sodium tungstate; dihydrogen peroxide; potassium carbonate; acetic acid; In methanol; 1,2-dimethoxyethane; toluene;
DOI:10.1021/jm030765s