p-Methoxyphenyl acrylate

Base Information

• Chemical Name: p-Methoxyphenyl acrylate
• CAS No.: 4513-44-4
• Molecular Formula: C10H10O3
• Molecular Weight: 178.188
• European Community (EC) Number: 224-834-1
• UNII: V726ZQW8JM
• DSSTox Substance ID: DTXSID60963344
• Nikkaji Number: J205.886C
• Wikidata: Q82945194
• Mol file: 4513-44-4.mol

Synonyms:p-Methoxyphenyl acrylate;4513-44-4;(4-methoxyphenyl) prop-2-enoate;V726ZQW8JM;2-Propenoic acid, 4-methoxyphenyl ester;4-METHOXYPHENYL PROP-2-ENOATE;4-methoxyphenyl acrylate;4-metho-xyphenylacrylate;UNII-V726ZQW8JM;SCHEMBL1061204;DTXSID60963344;Acrylic acid p-methoxyphenyl ester;EINECS 224-834-1

Chemical Property of p-Methoxyphenyl acrylate

Chemical Property:

• Vapor Pressure: 8.3E-12mmHg at 25°C
• Boiling Point: 283.8°Cat760mmHg
• Flash Point: 114.3°C
• PSA: 35.53000
• Density: 1.095g/cm³
• LogP: 1.78660
• XLogP3: 2.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 178.062994177
• Heavy Atom Count: 13
• Complexity: 181

Purity/Quality:

98%Min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=C(C=C1)OC(=O)C=C

Technology Process of p-Methoxyphenyl acrylate

There total 5 articles about p-Methoxyphenyl acrylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

4-methoxy-phenol (150-76-5) + acrylic acid (79-10-7) → 4-methoxyphenyl acrylate (4513-44-4)

Guidance literature:

acrylic acid; With thionyl chloride; for 0.5h; Reflux;

4-methoxy-phenol; In dichloromethane; for 1h; Reflux;

DOI:10.1002/bkcs.10067

Reference yield: 27.0%

1-methoxy-4-(prop-1-yn-1-yloxy)benzene (102508-25-8) → 4-methoxyphenyl acrylate (4513-44-4)

Guidance literature:

With 2,6-lutidine N-oxide; tetrafluoroboric acid diethyl ether; In 1,4-dioxane; at 80 ℃; for 7h;

DOI:10.1002/anie.201304813

Reference yield:

4-methoxy-phenol (150-76-5) + acryloyl chloride (814-68-6,25189-84-8) → 4-methoxyphenyl acrylate (4513-44-4)

Guidance literature:

DOI:10.1016/0040-4039(96)00115-3

upstream raw materials:

4-methoxy-phenol

acryloyl chloride

4'-methoxyphenyl 3-bromopropionate

acrylic acid