Technology Process of C19H20F3O4S(1-)*Na(1+)
There total 5 articles about C19H20F3O4S(1-)*Na(1+) which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
malonic acid dimethyl ester;
With
sodium methylate;
In
1,4-dioxane; methanol;
for 0.25h;
Reflux;
C15H17F3OS;
In
1,4-dioxane; methanol;
for 1h;
Reflux;
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: pyridine / dichloromethane / 3 h / 0 °C
2.1: 60percent sodium hydrate / N,N-dimethyl-formamide / 0.42 h / Inert atmosphere; Cooling with ice
2.2: 9 h / 10 - 90 °C
3.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / 0.67 h / -78 °C / Inert atmosphere
3.2: 7 h / -78 - 0 °C
4.1: 5,5-dimethyl-1,3-cyclohexadiene / 8 h / Reflux
5.1: sodium methylate / methanol; 1,4-dioxane / 0.25 h / Reflux
5.2: 1 h / Reflux
With
pyridine; oxalyl dichloride; sodium methylate; dimethyl sulfoxide;
In
1,4-dioxane; methanol; 5,5-dimethyl-1,3-cyclohexadiene; dichloromethane; N,N-dimethyl-formamide;
4.1: |Wittig Olefination;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / 0.67 h / -78 °C / Inert atmosphere
1.2: 7 h / -78 - 0 °C
2.1: 5,5-dimethyl-1,3-cyclohexadiene / 8 h / Reflux
3.1: sodium methylate / methanol; 1,4-dioxane / 0.25 h / Reflux
3.2: 1 h / Reflux
With
oxalyl dichloride; sodium methylate; dimethyl sulfoxide;
In
1,4-dioxane; methanol; 5,5-dimethyl-1,3-cyclohexadiene; dichloromethane;
2.1: |Wittig Olefination;
