3-[5-hydroxy-4-(4-methoxybenzyl)-3-trifluromethylpyrazol-1-yl]-propionitrile

Base Information

Chemical Name:3-[5-hydroxy-4-(4-methoxybenzyl)-3-trifluromethylpyrazol-1-yl]-propionitrile
CAS No.:1233840-52-2
Molecular Formula:C₁₅H₁₄F₃N₃O₂
Molecular Weight:325.29
Hs Code.:

Synonyms:3-[5-hydroxy-4-(4-methoxybenzyl)-3-trifluromethylpyrazol-1-yl]-propionitrile

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3-[5-hydroxy-4-(4-methoxybenzyl)-3-trifluromethylpyrazol-1-yl]-propionitrile

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Technology Process of 3-[5-hydroxy-4-(4-methoxybenzyl)-3-trifluromethylpyrazol-1-yl]-propionitrile

There total 1 articles about 3-[5-hydroxy-4-(4-methoxybenzyl)-3-trifluromethylpyrazol-1-yl]-propionitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: 353-07-1
3-hydrazinylpropanenitrile

: 121749-58-4
4,4,4-trifluoro-2-(4-methoxy-benzyl)-3-oxo-butyric acid ethyl ester

: 1233840-52-2
3-[5-hydroxy-4-(4-methoxybenzyl)-3-trifluromethylpyrazol-1-yl]-propionitrile

Guidance literature:: 3-hydrazinylpropanenitrile; 4,4,4-trifluoro-2-(4-methoxy-benzyl)-3-oxo-butyric acid ethyl ester; With acetic acid; at 50 - 80 ℃; for 5.25h; Cooling with ice water;

With water; for 0.0333333h; Product distribution / selectivity; Cooling with ice;