1,1,2-Triphenyl-propan-1-OL

Base Information

• Chemical Name: 1,1,2-Triphenyl-propan-1-OL
• CAS No.: 38610-96-7
• Molecular Formula: C₂₁H₂₀O
• Molecular Weight: 288.389
• European Community (EC) Number: 651-863-0
• Nikkaji Number: J2.945.508B
• Mol file: 38610-96-7.mol

Synonyms:1,1,2-TRIPHENYL-PROPAN-1-OL;1,1,2-triphenyl-1-propanol;SCHEMBL2238856;AKOS024322319

Chemical Property of 1,1,2-Triphenyl-propan-1-OL

Chemical Property:

• XLogP3: 4.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 4
• Exact Mass: 288.151415257
• Heavy Atom Count: 22
• Complexity: 301

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC(C1=CC=CC=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3)O

Technology Process of 1,1,2-Triphenyl-propan-1-OL

There total 9 articles about 1,1,2-Triphenyl-propan-1-OL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

benzophenone (119-61-9) + ethylbenzene (100-41-4,27536-89-6) → 1,1,2-triphenyl-1-propanol (38610-96-7)

Guidance literature:

With tris[2-phenylpyridinato-C²,N]iridium(III); potassium carbonate; triisopropylsilanethiol; In acetone; at 30 ℃; Inert atmosphere; Irradiation;

DOI:10.1021/acscatal.9b02401

Reference yield: 3.0%

phenylmagnesium bromide + 1-(3,5-Dimethyl-pyrazol-1-yl)-2-phenyl-propan-1-one → 1,2-diphenylpropan-1-one (2042-85-5) + 1,1,2-triphenyl-1-propanol (38610-96-7)

Guidance literature:

In diethyl ether; for 1h; Ambient temperature;

Reference yield:

benzophenone (119-61-9) + 1-dimethylstibanyl-1-phenylethane (872610-99-6) → 1,1,2-triphenyl-1-propanol (38610-96-7)

Guidance literature:

1-dimethylstibanyl-1-phenylethane; With Me₄ZnLi₂; In tetrahydrofuran; at -78 ℃; for 0.5h;

benzophenone; In tetrahydrofuran; at -78 - 20 ℃; for 0.5h;

DOI:10.1002/chem.201100265

upstream raw materials:

benzophenone

ethylbenzene

1,2-diphenylpropan-1-one

phenyllithium

Downstream raw materials:

1,1,2-triphenylprop-1-ene

(+/-)-methyl-(1.1.2-triphenyl-propyl)-ether

2,2,3-triphenyl-butyric acid