(S)-2-(1-(4-methoxyphenyl)ethyl)naphthalene

Base Information

• Chemical Name: (S)-2-(1-(4-methoxyphenyl)ethyl)naphthalene
• CAS No.: 1424035-17-5
• Molecular Formula: C₁₉H₁₈O
• Molecular Weight: 262.351
• Mol file: 1424035-17-5.mol

Synonyms:(S)-2-(1-(4-methoxyphenyl)ethyl)naphthalene

Chemical Property of (S)-2-(1-(4-methoxyphenyl)ethyl)naphthalene

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of (S)-2-(1-(4-methoxyphenyl)ethyl)naphthalene

There total 10 articles about (S)-2-(1-(4-methoxyphenyl)ethyl)naphthalene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

2,4,6-tris(4-methoxyphenyl)boroxine (7294-51-1) + (S)-1--(naphthalen--2--yl)ethyl pivalate → (S)-2-(1-(4-methoxyphenyl)ethyl)naphthalene (1424035-17-5)

Guidance literature:

With bis(1,5-cyclooctadiene)nickel ⁽⁰⁾; sodium methylate; In toluene; at 70 ℃; for 3h; Inert atmosphere; Glovebox;

DOI:10.1021/ja312087x

Reference yield: 61.0%

2-naphthylethylene (827-54-3,28406-56-6) + 4-methoxyphenylboronic acid (5720-07-0) → (S)-2-(1-(4-methoxyphenyl)ethyl)naphthalene (1424035-17-5)

Guidance literature:

With bis(1,5-cyclooctadiene)nickel⁽⁰⁾; C₃₃H₃₀N₂O₂; lithium tert-butoxide; In methanol; at 50 ℃; for 3h; enantioselective reaction; Inert atmosphere; Glovebox; Sealed tube;

DOI:10.1021/acs.joc.0c02556

Reference yield: 12.0%

O-(1-(naphthalen-2-yl)ethyl) benzoyl(phenyl)carbamothioate + 4-methoxyphenylzinc(II) methoxide → (S)-2-(1-(4-methoxyphenyl)ethyl)naphthalene (1424035-17-5) + (R)-2-(1-(4-methoxyphenyl)ethyl)naphthalene (1442898-25-0) + O-(1-(naphthalen-2-yl)ethyl) 4-methoxybenzothioate

Guidance literature:

O-(1-(naphthalen-2-yl)ethyl) benzoyl(phenyl)carbamothioate; With nickel(II) acetylacetonate monohydrate; Bathocuproine; magnesium chloride; In 1,4-dioxane; at 23 ℃; for 0.0833333h; Inert atmosphere; Sealed tube;

4-methoxyphenylzinc(II) methoxide; In tetrahydrofuran; 1,4-dioxane; at 23 ℃; for 12h; Inert atmosphere; Sealed tube;

DOI:10.1021/jacs.0c06904

upstream raw materials:

2,4,6-tris(4-methoxyphenyl)boroxine

(S)-1-(2-Naphthyl)ethanol

2-(2-naphthyl)ethanol

methyl 2-naphthyl ketone