(4-Chloro-phenyl)-dithiocarbamic acid (E)-but-2-enyl ester

Base Information

• Chemical Name: (4-Chloro-phenyl)-dithiocarbamic acid (E)-but-2-enyl ester
• CAS No.: 133465-03-9
• Molecular Formula: C₁₁H₁₂ClNS₂
• Molecular Weight: 257.808
• Mol file: 133465-03-9.mol

Synonyms:(4-Chloro-phenyl)-dithiocarbamic acid (E)-but-2-enyl ester

Chemical Property of (4-Chloro-phenyl)-dithiocarbamic acid (E)-but-2-enyl ester

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of (4-Chloro-phenyl)-dithiocarbamic acid (E)-but-2-enyl ester

There total 1 articles about (4-Chloro-phenyl)-dithiocarbamic acid (E)-but-2-enyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

carbon disulfide (75-15-0,12122-00-8) + trans-but-2-enyl chloride (4894-61-5) + 4-chloro-aniline (106-47-8) → (4-Chloro-phenyl)-dithiocarbamic acid (E)-but-2-enyl ester (133465-03-9)

Guidance literature:

With sodium hydroxide; Yield given. Multistep reaction; 1a) DMSO, RT, 0.5 h, 1b) RT, 0.5 h, 2) 0 to 20 deg C, 2 h;

DOI:10.1055/s-1991-26400

Reference yield: 67.0%

(4-Chloro-phenyl)-dithiocarbamic acid (E)-but-2-enyl ester (133465-03-9) + methyl iodide (74-88-4) → C12H14ClNS2 (133465-13-1)

Guidance literature:

With sodium hydroxide; In N,N-dimethyl-formamide; 1) RT, 0.5 h, 2) 0 to 20 deg C, 1 h;

DOI:10.1055/s-1991-26400

Reference yield:

(4-Chloro-phenyl)-dithiocarbamic acid (E)-but-2-enyl ester (133465-03-9) → (4-Chloro-phenyl)-(1-methyl-allyl)-dithiocarbamic acid methyl ester (133465-24-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 67 percent / 1) NaOH / dimethylformamide / 1) RT, 0.5 h, 2) 0 to 20 deg C, 1 h

2: 65 percent / dichlorobis(benzonitrile)palladium(II) / dioxane / 20 h / Heating

With sodium hydroxide; bis(benzonitrile)palladium(II) dichloride; In 1,4-dioxane; N,N-dimethyl-formamide;

DOI:10.1055/s-1991-26400

upstream raw materials:

carbon disulfide

trans-but-2-enyl chloride

4-chloro-aniline

Downstream raw materials:

C₁₂H₁₄ClNS₂

(4-Chloro-phenyl)-(1-methyl-allyl)-dithiocarbamic acid methyl ester