Technology Process of silver 3-chloro-5-phenylisothiazole-4-carboxylate
There total 1 articles about silver 3-chloro-5-phenylisothiazole-4-carboxylate which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
potassium hydroxide;
In
water;
addn. of a soln. of KOH in water to a stirred mixt. of acid and water, stirring at 20°C, addn. of a soln. of AgNO3 in water; filtration, washing with water, acetone, drying in vac. at 80°C for 12 h;
DOI:10.1039/b702154b
- Guidance literature:
-
With
bromine;
In
tetrachloromethane;
at 20 ℃;
for 1h;
DOI:10.1039/b702154b
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 80 percent / Br2 / CCl4 / 1 h / 20 °C
2: 96 percent / K2CO3 / Pd(OAc)2 / dimethylformamide / 1.25 h / 100 °C
3: 95 percent / aq. KOH / 24 h / 200 °C / 12929 Torr
4: 85 percent / POBr3 / 24 h / 100 °C
With
potassium hydroxide; bromine; potassium carbonate; phosphorus(V) oxybromide;
palladium diacetate;
In
tetrachloromethane; N,N-dimethyl-formamide;
1: Hunsdiecker reaction / 2: Suzuki reaction;
DOI:10.1039/b702154b
