3-chloro-4,5-diphenylisothiazole

Base Information

• Chemical Name: 3-chloro-4,5-diphenylisothiazole
• CAS No.: 942227-82-9
• Molecular Formula: C₁₅H₁₀ClNS
• Molecular Weight: 271.77
• Mol file: 942227-82-9.mol

Synonyms:3-chloro-4,5-diphenylisothiazole

Chemical Property of 3-chloro-4,5-diphenylisothiazole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-chloro-4,5-diphenylisothiazole

There total 8 articles about 3-chloro-4,5-diphenylisothiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

3-chloro-4-iodo-5-phenylisothiazole (942227-81-8) + tributylphenylstannane (960-16-7) → 3-chloro-4,5-diphenylisothiazole (942227-82-9)

Guidance literature:

palladium diacetate; In N,N-dimethyl-formamide; at 100 ℃; for 0.416667h;

DOI:10.1039/b702154b

Reference yield: 98.0%

3-chloro-4-iodo-5-phenylisothiazole (942227-81-8) + phenylboronic acid (98-80-6) → 3-chloro-4,5-diphenylisothiazole (942227-82-9)

Guidance literature:

With potassium carbonate; palladium diacetate; In N,N-dimethyl-formamide; at 100 ℃; for 0.666667h;

DOI:10.1039/b702154b

Reference yield: 98.0%

3-hydroxy-4,5-diphenylisothiazole (37120-50-6) → 3-chloro-4,5-diphenylisothiazole (942227-82-9)

Guidance literature:

With trichlorophosphate; at 150 ℃; for 72h;

DOI:10.1039/b702154b

upstream raw materials:

4-bromo-3-chloro-5-phenylisothiazole

phenylboronic acid

3-chloro-4-iodo-5-phenylisothiazole

tributylphenylstannane

Downstream raw materials:

3-hydroxy-4,5-diphenylisothiazole

3-amino-4,5-diphenylisothiazole

3-bromo-4,5-diphenylisothiazole

3,4,5-Triphenylisothiazole