(4-(13-hydroxy-2,5,8,11-tetraoxatridecyl)phenyl)(phenyl)methanone

Base Information

• Chemical Name: (4-(13-hydroxy-2,5,8,11-tetraoxatridecyl)phenyl)(phenyl)methanone
• CAS No.: 244254-30-6
• Molecular Formula: C₂₂H₂₈O₆
• Molecular Weight: 388.461
• Mol file: 244254-30-6.mol

Synonyms:(4-(13-hydroxy-2,5,8,11-tetraoxatridecyl)phenyl)(phenyl)methanone

Chemical Property of (4-(13-hydroxy-2,5,8,11-tetraoxatridecyl)phenyl)(phenyl)methanone

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of (4-(13-hydroxy-2,5,8,11-tetraoxatridecyl)phenyl)(phenyl)methanone

There total 1 articles about (4-(13-hydroxy-2,5,8,11-tetraoxatridecyl)phenyl)(phenyl)methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.8%

Tetraethylene glycol (112-60-7) + 4-(bromomethyl)benzophenone (32752-54-8) → (4-(13-hydroxy-2,5,8,11-tetraoxatridecyl)phenyl)(phenyl)methanone (244254-30-6)

Guidance literature:

Tetraethylene glycol; With sodium hydride; In tetrahydrofuran; at 4 - 20 ℃; for 1h;

4-(bromomethyl)benzophenone; In tetrahydrofuran; at 20 ℃; for 16h;

Reference yield: 55.0%

(4-(13-hydroxy-2,5,8,11-tetraoxatridecyl)phenyl)(phenyl)methanone (244254-30-6) + 2-chloromethylnicotinic acid → 2-(15-(4-benzoylphenyl)-2,5,8,11,14-pentaoxapentadecyl)nicotinic acid

Guidance literature:

(4-(13-hydroxy-2,5,8,11-tetraoxatridecyl)phenyl)(phenyl)methanone; With sodium hydride; In tetrahydrofuran; at 0 ℃; for 0.5h; Inert atmosphere;

2-chloromethylnicotinic acid; In tetrahydrofuran; at 0 - 20 ℃; Inert atmosphere;

DOI:10.1021/jacs.0c12246

Reference yield:

(4-(13-hydroxy-2,5,8,11-tetraoxatridecyl)phenyl)(phenyl)methanone (244254-30-6) + methanesulfonyl chloride (124-63-0) → C23H30O8S

Guidance literature:

In dichloromethane; at 0 - 20 ℃; for 8h;

upstream raw materials:

Tetraethylene glycol

4-(bromomethyl)benzophenone