tert-butyl N-(2,3,4-trifluoro-5-nitrophenyl)carbamate

Base Information

Chemical Name:tert-butyl N-(2,3,4-trifluoro-5-nitrophenyl)carbamate
CAS No.:535170-16-2
Molecular Formula:C₁₁H₁₁F₃N₂O₄
Molecular Weight:292.215
Hs Code.:
DSSTox Substance ID:DTXSID601150123

Synonyms:535170-16-2;DTXSID601150123;Carbamic acid, (2,3,4-trifluoro-5-nitrophenyl)-, 1,1-dimethylethyl ester

Suppliers and Price of tert-butyl N-(2,3,4-trifluoro-5-nitrophenyl)carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of tert-butyl N-(2,3,4-trifluoro-5-nitrophenyl)carbamate

Chemical Property:

XLogP3:2.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:3
Exact Mass:292.06709132
Heavy Atom Count:20
Complexity:383

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC1=CC(=C(C(=C1F)F)F)[N+](=O)[O-]

Technology Process of tert-butyl N-(2,3,4-trifluoro-5-nitrophenyl)carbamate

There total 4 articles about tert-butyl N-(2,3,4-trifluoro-5-nitrophenyl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 197520-71-1
2,3,4-trifluoro-5-nitro-benzoic acid

: 535170-16-2
tert-butyl 5-nitro-2,3,4-trifluorophenylcarbamate

Guidance literature:: Multi-step reaction with 3 steps

1: oxalyl chloride; DMF / CH₂Cl₂ / 20 °C

2: sodium azide / CH₂Cl₂; dimethylformamide / 20 °C

3: CH₂Cl₂; dimethylformamide / Heating

With sodium azide; oxalyl dichloride; N,N-dimethyl-formamide; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jm0205090

Reference yield:

: 61079-72-9
2,3,4,-trifluorobenzoic acid

: 535170-16-2
tert-butyl 5-nitro-2,3,4-trifluorophenylcarbamate

Guidance literature:: Multi-step reaction with 4 steps

1: 85 percent / KNO₃; conc. H₂SO₄ / 20 °C

2: oxalyl chloride; DMF / CH₂Cl₂ / 20 °C

3: sodium azide / CH₂Cl₂; dimethylformamide / 20 °C

4: CH₂Cl₂; dimethylformamide / Heating

With sodium azide; oxalyl dichloride; sulfuric acid; potassium nitrate; N,N-dimethyl-formamide; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jm0205090

Reference yield:

: 2,3,4-trifluoro-5-nitro-benzoyl chloride

: 535170-16-2
tert-butyl 5-nitro-2,3,4-trifluorophenylcarbamate

Guidance literature:: Multi-step reaction with 2 steps

1: sodium azide / CH₂Cl₂; dimethylformamide / 20 °C

2: CH₂Cl₂; dimethylformamide / Heating

With sodium azide; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jm0205090