Technology Process of C35H28N4O8
There total 9 articles about C35H28N4O8 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
4-aminopyrido[2,3-d]pyrimidin-5(8H)-one;
With
N,O-bis-(trimethylsilyl)-acetamide;
In
1,2-dichloro-ethane;
at 75 ℃;
for 2h;
1-O-acetyl-2,3,5-tri-O-benzoyl-4-C-vinyl-D-ribofuranose;
With
trimethylsilyl trifluoromethanesulfonate;
In
1,2-dichloro-ethane;
for 72h;
Further stages.;
Heating;
DOI:10.1021/jm000073t
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: pyridine / 18 h / 20 °C
2.1: TFA; water / 2 h / 0 °C
3.1: pyridine / 20 h / 20 °C
4.1: AcOH; H2SO4 / 6 h / 20 °C
5.1: N,O-bis(trimethylsilyl)acetamide / 1,2-dichloro-ethane / 2 h / 75 °C
5.2: trimethylsilyl triflate / 1,2-dichloro-ethane / 72 h / Heating
With
pyridine; N,O-bis-(trimethylsilyl)-acetamide; sulfuric acid; water; acetic acid; trifluoroacetic acid;
In
1,2-dichloro-ethane;
5.2: Vorbrueggen reaction;
DOI:10.1021/jm000073t
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: 80 percent / acetonitrile / 20 h / Heating
2.1: 89 percent / 2-ethoxy-ethanol / 30 h / Heating
3.1: N,O-bis(trimethylsilyl)acetamide / 1,2-dichloro-ethane / 2 h / 75 °C
3.2: trimethylsilyl triflate / 1,2-dichloro-ethane / 72 h / Heating
With
N,O-bis-(trimethylsilyl)-acetamide;
In
2-ethoxy-ethanol; 1,2-dichloro-ethane; acetonitrile;
3.2: Vorbrueggen reaction;
DOI:10.1021/jm000073t
![4-aminopyrido[2,3-d]pyrimidin-5(8H)-one](/Databaselist/images/loading.webp)
