98651-70-8

Usage

Uses

Used in Pharmaceutical Industry:
2-amino-4-methoxypyridine-3-carbonitrile is used as a building block in the synthesis of pharmaceuticals for its potential biological activities, such as antimicrobial and anticancer properties. Its versatile reactivity allows for the development of new drugs with improved efficacy and safety profiles.
Used in Agrochemical Industry:
2-amino-4-methoxypyridine-3-carbonitrile is also used as a building block in the synthesis of agrochemicals, contributing to the development of novel pesticides and other agricultural chemicals. Its potential biological activity can be harnessed to create more effective and environmentally friendly products for crop protection and other agricultural applications.

InChI:InChI=1/C7H7N3O/c1-11-6-2-3-10-7(9)5(6)4-8/h2-3H,1H3,(H2,9,10)

Upstream product

• 95689-38-6 1,1-dicyano-4-(N,N-dimethylamino)-2-methoxy-1,3-butadiene 
• 5417-82-3 (1-ethoxyethylidene)malononitrile 

Downstream Products

• 21642-98-8 4-methoxy-2-oxo-1,2-dihydropyridine-3-carbonitrile 
• 306960-29-2 2-amino-3-cyano-1H-pyrid-4-one 
• 834869-04-4 7-Methoxy-imidazo[1,2-a]pyridine-8-carbonitrile 
• 306960-30-5 4-amino-5-oxo-pyrido[2,3-d]pyrimidine 
• 1152617-02-1 7-hydroxy-3-phenylimidazo[1,2-a]pyridine-8-carbonitrile 
• 1152617-29-2 7-hydroxyimidazo[1,2-a]pyridine-8-carbonitrile 
• 852222-48-1 4-amino-8-(4-amino-phenyl)-8H-pyrido[2,3-d]pyrimidin-5-one 
• 852222-46-9 4-amino-8-(4-nitro-phenyl)-8H-pyrido[2,3-d]pyrimidin-5-one 
• 338412-35-4 N'-(3-cyano-4-methoxy-pyridin-2-yl)-N,N-dimethyl-formamidine 
• 306960-37-2 8-{3-[bis-(4-methoxy-phenyl)-phenyl-methoxy]-5-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-oxo-tetrahydro-furan-2-yl}-4-{[bis-(4-methoxy-phenyl)-phenyl-methyl]-amino}-8H-pyrido[2,3-d]pyrimidin-5-one 
• 1053475-66-3 8-{3-[bis-(4-methoxy-phenyl)-phenyl-methoxy]-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl}-4-{[bis-(4-methoxy-phenyl)-phenyl-methyl]-amino}-8H-pyrido[2,3-d]pyrimidin-5-one 
• 385435-85-8 C₄₁H₃₂N₄O₁₀ 
• 1053698-55-7 C₃₅H₂₆N₄O₈ 
• 1053257-01-4 C₃₆H₃₀N₄O₈ 

Relevant academic research and scientific papers

INDOLE AND BENZOXAZINE DERIVATIVES AS MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS

The present invention relates to novel indole and benzoxazine derivatives which are positive allosteric modulators of the metabotropic glutamate receptor subtype 2 ("mGluR2") and which are useful for the treatment or prevention of neurological and psychiatric disorders associated with glutamate dysfunction and diseases in which the mGluR2 subtype of metabotropic receptors is involved. The invention is also directed to pharmaceutical compositions comprising such compounds, to processes to prepare such compounds and compositions, and to the use of such compounds for the prevention or treatment of neurological and psychiatric disorders and diseases in which mGluR2 is involved.

IMIDAZO[1,2-A]PYRIDINE DERIVATIVES AND THEIR USE AS POSITIVE ALLOSTERIC MODULATORS OF MGLUR2 RECEPTORS

The present invention relates to novel compounds, in particular novel imidazo[1,2-a]piridine derivatives according to Formula (I) wherein all radicals are as defined in the application and claims. The compounds according to the invention are positive allosteric modulators of metabotropic receptors - subtype 2 ("mGluR2") which are useful for the treatment or prevention of neurological and psychiatric disorders associated with glutamate dysfunction and diseases in which the mGluR2 subtype of metabotropic receptors is involved. In particular, such diseases are central nervous system disorders selected from the group of anxiety, schizophrenia, migraine, depression, and epilepsy. The invention is also directed to pharmaceutical compositions and processes to prepare such compounds and compositions, as well as to the use of such compounds for the prevention and treatment of such diseases in which mGluR2 is involved.

SULFONAMIDES

The invention relates to compounds of formula (I) in which R6, R7, R8, R9 and X have the meanings cited in Claim 1. These compounds are inhibitors of tyrosinkinases, particularly TIE-2, and Raf kinases and can, among other things, be used for treating tumors.