[5-(2-Methyl-imidazo[1,2-a]pyridin-3-yl)-[1,3,4]oxadiazol-2-yl]-phenyl-amine

Base Information

Chemical Name:[5-(2-Methyl-imidazo[1,2-a]pyridin-3-yl)-[1,3,4]oxadiazol-2-yl]-phenyl-amine
CAS No.:144835-80-3
Molecular Formula:C₁₆H₁₃N₅O
Molecular Weight:291.312
Hs Code.:

Synonyms:[5-(2-Methyl-imidazo[1,2-a]pyridin-3-yl)-[1,3,4]oxadiazol-2-yl]-phenyl-amine

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Chemical Property of [5-(2-Methyl-imidazo[1,2-a]pyridin-3-yl)-[1,3,4]oxadiazol-2-yl]-phenyl-amine

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Technology Process of [5-(2-Methyl-imidazo[1,2-a]pyridin-3-yl)-[1,3,4]oxadiazol-2-yl]-phenyl-amine

There total 3 articles about [5-(2-Methyl-imidazo[1,2-a]pyridin-3-yl)-[1,3,4]oxadiazol-2-yl]-phenyl-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 105-36-2
ethyl bromoacetate

: 144835-73-4
C₁₆H₁₅N₅OS

: 144835-80-3
[5-(2-Methyl-imidazo[1,2-a]pyridin-3-yl)-[1,3,4]oxadiazol-2-yl]-phenyl-amine

Guidance literature:: With sodium acetate; In ethanol; for 4h; Heating;
DOI:10.1002/ardp.19923250920

Reference yield:

: 2549-19-1
ethyl 2-methylimidazo[1,2-a]pyridine-3-carboxylate

: 144835-80-3
[5-(2-Methyl-imidazo[1,2-a]pyridin-3-yl)-[1,3,4]oxadiazol-2-yl]-phenyl-amine

Guidance literature:: Multi-step reaction with 3 steps

1: 80 percent / H₂NNH₂*H₂O / aq. ethanol / 5 h / Heating

2: 96 percent / ethanol / 3 h / Heating

3: 82 percent / CH₃COONa / ethanol / 4 h / Heating

With sodium acetate; hydrazine hydrate; In ethanol;
DOI:10.1002/ardp.19923250920

Reference yield:

: 144835-67-6
2-methyl-4H-imidazo[1,2-a]pyridine-3-carbohydrazide

: 144835-80-3
[5-(2-Methyl-imidazo[1,2-a]pyridin-3-yl)-[1,3,4]oxadiazol-2-yl]-phenyl-amine

Guidance literature:: Multi-step reaction with 2 steps

1: 96 percent / ethanol / 3 h / Heating

2: 82 percent / CH₃COONa / ethanol / 4 h / Heating

With sodium acetate; In ethanol;
DOI:10.1002/ardp.19923250920