1-([5'-([(2S)-2-(phenoxymethyl)pyrrolidin-1-yl]sulfonyl)-2'-oxospiro[1,3-dioxane-2,3'-indol]-1'(2'H)-yl]methyl)cyclohexanecarbonitrile

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Chemical Name:1-([5'-([(2S)-2-(phenoxymethyl)pyrrolidin-1-yl]sulfonyl)-2'-oxospiro[1,3-dioxane-2,3'-indol]-1'(2'H)-yl]methyl)cyclohexanecarbonitrile
CAS No.:1202497-88-8
Molecular Formula:C₃₀H₃₅N₃O₆S
Molecular Weight:565.69
Hs Code.:

Synonyms:1-([5'-([(2S)-2-(phenoxymethyl)pyrrolidin-1-yl]sulfonyl)-2'-oxospiro[1,3-dioxane-2,3'-indol]-1'(2'H)-yl]methyl)cyclohexanecarbonitrile

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Chemical Property of 1-([5'-([(2S)-2-(phenoxymethyl)pyrrolidin-1-yl]sulfonyl)-2'-oxospiro[1,3-dioxane-2,3'-indol]-1'(2'H)-yl]methyl)cyclohexanecarbonitrile

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Technology Process of 1-([5'-([(2S)-2-(phenoxymethyl)pyrrolidin-1-yl]sulfonyl)-2'-oxospiro[1,3-dioxane-2,3'-indol]-1'(2'H)-yl]methyl)cyclohexanecarbonitrile

There total 1 articles about 1-([5'-([(2S)-2-(phenoxymethyl)pyrrolidin-1-yl]sulfonyl)-2'-oxospiro[1,3-dioxane-2,3'-indol]-1'(2'H)-yl]methyl)cyclohexanecarbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 869223-94-9
(S)-1-{[1',2'-dihydro-2'-oxospiro(1,3-dioxane-2,3'-[3H]indol)-5'-yl]sulfonyl}-2-(phenoxymethyl)-pyrrolidine

: 112905-95-0
1-(chloromethyl)cyclohexanecarbonitrile

: 1202497-88-8
1-([5'-([(2S)-2-(phenoxymethyl)pyrrolidin-1-yl]sulfonyl)-2'-oxospiro[1,3-dioxane-2,3'-indol]-1'(2'H)-yl]methyl)cyclohexanecarbonitrile

Guidance literature:: (S)-1-{[1',2'-dihydro-2'-oxospiro(1,3-dioxane-2,3'-[3H]indol)-5'-yl]sulfonyl}-2-(phenoxymethyl)-pyrrolidine; With potassium tert-butylate; In dimethyl sulfoxide; for 0.333333h; Inert atmosphere;

1-(chloromethyl)cyclohexanecarbonitrile; In dimethyl sulfoxide; at 185 ℃; for 21h; Inert atmosphere;
DOI:10.1016/j.bmc.2009.09.036