o-Hydroxycrotonophenone

Base Information

Chemical Name:o-Hydroxycrotonophenone
CAS No.:15811-69-5
Molecular Formula:C₁₀H₁₀O₂
Molecular Weight:162.188
Hs Code.:
DSSTox Substance ID:DTXSID201271575

Synonyms:o-hydroxycrotonophenone;SCHEMBL14416844;DTXSID201271575;15811-69-5;2-Buten-1-one, 1-(2-hydroxyphenyl)-, (E)-

Suppliers and Price of o-Hydroxycrotonophenone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of o-Hydroxycrotonophenone

Chemical Property:

XLogP3:2.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:162.068079557
Heavy Atom Count:12
Complexity:184

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC=CC(=O)C1=CC=CC=C1O
Isomeric SMILES:C/C=C/C(=O)C1=CC=CC=C1O

Technology Process of o-Hydroxycrotonophenone

There total 7 articles about o-Hydroxycrotonophenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

: 118-93-4,104809-67-8
o-hydroxyacetophenone

: 75-07-0,9002-91-9
acetaldehyde

: 15811-69-5
1-(2-hydroxy-phenyl)-but-2t-en-1-one

Guidance literature:: barium dihydroxide; In ethanol; for 4h; Heating;
DOI:10.1016/S0040-4039(01)81030-3

Reference yield:

: (S)-3-Hydroxy-1-(2-hydroxy-phenyl)-butan-1-one

: 15811-69-5
1-(2-hydroxy-phenyl)-but-2t-en-1-one

: (+)-(R)-2,3-dihydro-2-methyl-4H-1-benzopyran

Guidance literature:: With triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; at 0 ℃;
DOI:10.1016/S0040-4039(01)00567-6

Reference yield:

: 351458-96-3
3-(tert-butyl-dimethyl-silanyloxy)-1-(2-hydroxy-phenyl)-butan-1-one

: 15811-69-5
1-(2-hydroxy-phenyl)-but-2t-en-1-one

Guidance literature:: Multi-step reaction with 2 steps

1: p-TsOH / tetrahydrofuran; H₂O / 55 °C

2: PPh₃; DEAD / tetrahydrofuran / 0 °C

With toluene-4-sulfonic acid; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; water; 2: intramolecular Mitsunobu cyclization;
DOI:10.1016/S0040-4039(01)00567-6