4-(2,6-Dichloro-4-nitrophenyl)sulfonylmorpholine

Base Information

Chemical Name:4-(2,6-Dichloro-4-nitrophenyl)sulfonylmorpholine
CAS No.:74875-18-6
Molecular Formula:C₁₀H₁₀Cl₂N₂O₅S
Molecular Weight:341.172
Hs Code.:
DSSTox Substance ID:DTXSID701229929

Synonyms:74875-18-6;DTXSID701229929;4-[(2,6-Dichloro-4-nitrophenyl)sulfonyl]morpholine

Suppliers and Price of 4-(2,6-Dichloro-4-nitrophenyl)sulfonylmorpholine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of 4-(2,6-Dichloro-4-nitrophenyl)sulfonylmorpholine

Chemical Property:

XLogP3:1.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:2
Exact Mass:339.9687480
Heavy Atom Count:20
Complexity:445

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1COCCN1S(=O)(=O)C2=C(C=C(C=C2Cl)[N+](=O)[O-])Cl

Technology Process of 4-(2,6-Dichloro-4-nitrophenyl)sulfonylmorpholine

There total 1 articles about 4-(2,6-Dichloro-4-nitrophenyl)sulfonylmorpholine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 110-91-8,99108-56-2
morpholine

: 74875-17-5
2,6-dichloro-4-nitrobenzenesulfonyl chloride

: 74875-18-6
3,5-dichloro-4-(morpholinylsulfonyl)nitrobenzene

Guidance literature:: In diethyl ether; for 3h; Heating;
DOI:10.1021/jm00184a005

Reference yield: 73.0%

: 74875-18-6
3,5-dichloro-4-(morpholinylsulfonyl)nitrobenzene

: 74875-19-7
3,5-dichloro-4-(morpholinylsulfonyl)aniline

Guidance literature:: With hydrogenchloride; tin(ll) chloride; for 1.25h; Heating;
DOI:10.1021/jm00184a005

Reference yield:

: 74875-18-6
3,5-dichloro-4-(morpholinylsulfonyl)nitrobenzene

: 74875-26-6
2-[3,5-Dichloro-4-(morpholine-4-sulfonyl)-phenyl]-2H-[1,2,4]triazine-3,5-dione

Guidance literature:: Multi-step reaction with 5 steps

1: 73 percent / SnCl₂*2H₂O, conc. aq. HCl / 1.25 h / Heating

2: 1.) 6 N aq. HCl, NaNO₂, 2.) pyridine / 1.) from 0 to 5 deg C, 2.) RT, 16 h

3: NaOAc, AcOH / 7 h / Heating

4: aq. HCl / acetic acid / 1.5 h / Heating

5: 68 percent / thioglycolic acid / 2 h / 165 °C

With pyridine; hydrogenchloride; sodium acetate; acetic acid; mercaptoacetic acid; tin(ll) chloride; sodium nitrite; In acetic acid;
DOI:10.1021/jm00184a005