3-ethoxy-2-((6-(4-fluorophenyl)pyridin3-yl)methoxy)-2-methyl-3-oxopropanoic acid

Base Information

Chemical Name:3-ethoxy-2-((6-(4-fluorophenyl)pyridin3-yl)methoxy)-2-methyl-3-oxopropanoic acid
CAS No.:1219005-60-3
Molecular Formula:C₁₈H₁₈FNO₅
Molecular Weight:347.343
Hs Code.:

Synonyms:3-ethoxy-2-((6-(4-fluorophenyl)pyridin3-yl)methoxy)-2-methyl-3-oxopropanoic acid

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Chemical Property of 3-ethoxy-2-((6-(4-fluorophenyl)pyridin3-yl)methoxy)-2-methyl-3-oxopropanoic acid

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Technology Process of 3-ethoxy-2-((6-(4-fluorophenyl)pyridin3-yl)methoxy)-2-methyl-3-oxopropanoic acid

There total 1 articles about 3-ethoxy-2-((6-(4-fluorophenyl)pyridin3-yl)methoxy)-2-methyl-3-oxopropanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 1219005-59-0
diethyl ((6-(4-fluorophenyl)pyridin-3-yl)methoxy)(methyl)malonate

: 1219005-60-3
3-ethoxy-2-((6-(4-fluorophenyl)pyridin3-yl)methoxy)-2-methyl-3-oxopropanoic acid

Guidance literature:: diethyl ((6-(4-fluorophenyl)pyridin-3-yl)methoxy)(methyl)malonate; With water; potassium hydroxide; In ethanol; at 25 ℃;

With ammonium chloride; In water;

Reference yield: 77.0%

: 154016-48-5
(5-methyl-3-isoxazolyl)methylamine

: 1219005-60-3
3-ethoxy-2-((6-(4-fluorophenyl)pyridin3-yl)methoxy)-2-methyl-3-oxopropanoic acid

: 1219005-61-4
ethyl 2-((6-(4-fluorophenyl)pyridin-3-yl)methoxy)-2-methyl-3-(((5-methylisoxazol-3-yl)methyl)amino)-3-oxopropanoate

Guidance literature:: 3-ethoxy-2-((6-(4-fluorophenyl)pyridin3-yl)methoxy)-2-methyl-3-oxopropanoic acid; With N-ethyl-N,N-diisopropylamine; HATU; In dichloromethane; N,N-dimethyl-formamide; at 0 ℃; for 0.25h; Inert atmosphere;

(5-methyl-3-isoxazolyl)methylamine; In dichloromethane; N,N-dimethyl-formamide; at 0 - 25 ℃; Inert atmosphere;