154016-48-5

Usage

Uses

Used in Pharmaceutical Industry:
(5-Methyl-3-isoxazolyl)methylamine is used as a chemical intermediate for the synthesis of various drugs and compounds, particularly those targeting neurological disorders. Its unique structure allows for the development of medications with potential therapeutic effects on the nervous system.
Used in Agrochemical Production:
MIMA serves as a building block in the creation of agrochemicals, contributing to the development of products that enhance crop protection and yield.
Used in Fine Chemicals Synthesis:
(5-Methyl-3-isoxazolyl)methylamine is utilized in the production of fine chemicals, which are high-purity chemicals used in various applications, including research, pharmaceuticals, and specialty industries.
It is important to handle and store MIMA with proper safety precautions due to its potential hazards, ensuring that it is managed responsibly in both industrial and laboratory settings.

InChI:InChI=1/C5H8N2O/c1-4-2-5(3-6)7-8-4/h2H,3,6H2,1H3

Upstream product

• 35166-33-7 (5-methyl-isoxazol-3-yl)-methanol 
• 109-80-8 1.3-propanedithiol 
• 154016-53-2 3-(azidomethyl)-5-methylisoxazole 
• 39499-34-8 5-methyl-3-isoxazolyl chloride 
• 3445-52-1 5-methyl-isoxazole-3-carbothioic acid amide 
• 615-79-2 ethyl 2,4-diketopentanoate 
• 130628-75-0 3-(bromomethyl)-5-methylisoxazole 
• 3209-72-1 ethyl 5-methylisoxazole-3-carboxylate 
• 57351-99-2 5-methyl-1,2-oxazole-3-carbonitrile 

Downstream Products

• 1344700-34-0 3-({[N-(biphenyl-4-ylcarbonyl)-O-ethyl-N-methyl-3-oxoseryl]amino}methyl)-5-methyl-1,2-oxazole 
• 1344707-44-3 (R/S)-2-hydroxy-N-((5-methylisoxazol-3-yl)methyl)-2-(4-(5-(3-phenyl-4-(trifluoromethyl)isoxazol-5-yl)-1,2,4-oxadiazol-3-yl)phenyl)acetamide 
• 1253299-02-3 N-[(5-methylisoxazol-3-yl)methyl]-2,4-diphenylthiazole-5-carboxamide 
• 1251463-33-8 N-[(5-methyl-isoxazol-3-yl)methyl]-6-(2,2,2-trifluoroethoxy)-N'-[3-(trifluoromethyl)phenyl]pyrimidine-2,4-diamine 
• 1219005-61-4 ethyl 2-((6-(4-fluorophenyl)pyridin-3-yl)methoxy)-2-methyl-3-(((5-methylisoxazol-3-yl)methyl)amino)-3-oxopropanoate 
• 1219005-58-9 methyl 2-(biphenyl-4-ylmethoxy)-2-methyl-3-(((5-methylisoxazol-3-yl)methyl)amino)-3-oxopropanoate 
• 1208146-92-2 C₂₃H₁₇Cl₂N₅O₂ 
• 1202927-42-1 2-(1-(3,4-difluorobenzyl)-5-oxo-1H-1,2,4-triazol-4(5H)-yl)-N-((5-methylisoxazol-3-yl)methyl)isonicotinamide 
• 943002-46-8 tert-butyl N-[2-[[4-[3-methyl-5-[[(5-methyl-1,2-oxazol-3-yl)methylamino]methyl]pyridin-2-yl]benzoyl]amino]phenyl]carbamate 

Relevant academic research and scientific papers

Reactions of β-diketone compounds with nitriles catalyzed by Lewis acids: A simple approach to β-enaminone synthesis

Aluminium chloride selectively promoted the nucleophilic attack of β-diketone compounds with nitriles to give enaminones. Moreover a plausible mechanism for this transformation was given.

SPIROHYDANTOIN COMPOUNDS AND THEIR USE AS SELECTIVE ANDROGEN RECEPTOR MODULATORS

The present invention relates to a compound of formula (1-1 ) in free form or in pharmaceutically acceptable salt form in which the substituents are as defined in the specification; to its preparation, to its use as a medicament and to medicaments comprising it. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.

Substituted imidazo [1,5-a] pyrimido [5,4-d] [1] benzazepine derivatives

The present invention is a compound of formula wherein R1 is halogen or lower alkyl; R2 is hydrogen, lower alkyl, cycloalkyl, —(CH2)m-phenyl, wherein the phenyl ring may be substituted by lower alkoxy, or is —(CH2)m-indolyl; R3 is —C(O)O-lower alkyl, —C(O)OH, or a five membered heteroaromatic group, which rings may be substituted by lower alkyl or cycloalkyl; n is 0, 1 or 2; m is 0, 1 or 2; or a pharmaceutically acceptable acid addition salt thereof. Compound I shows high affinity and selectivity for GALA A α5 receptor binding sites.

Regioselective syntheses of 3-aminomethyl-5-substituted isoxazoles: A facile and chemoselective reduction of azide to amino by sodium borohydride using 1,3-propanedithiol as a catalyst

A series of isoxazole azides were reduced selectively to isoxazole amines in quantitative yield by sodium borohydride using 1,3-propanedithiol as a catalyst.