ethyl 2-((6-(4-fluorophenyl)pyridin-3-yl)methoxy)-2-methyl-3-(((5-methylisoxazol-3-yl)methyl)amino)-3-oxopropanoate

Base Information

Chemical Name:ethyl 2-((6-(4-fluorophenyl)pyridin-3-yl)methoxy)-2-methyl-3-(((5-methylisoxazol-3-yl)methyl)amino)-3-oxopropanoate
CAS No.:1219005-61-4
Molecular Formula:C₂₃H₂₄FN₃O₅
Molecular Weight:441.459
Hs Code.:

Synonyms:ethyl 2-((6-(4-fluorophenyl)pyridin-3-yl)methoxy)-2-methyl-3-(((5-methylisoxazol-3-yl)methyl)amino)-3-oxopropanoate

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Chemical Property of ethyl 2-((6-(4-fluorophenyl)pyridin-3-yl)methoxy)-2-methyl-3-(((5-methylisoxazol-3-yl)methyl)amino)-3-oxopropanoate

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Technology Process of ethyl 2-((6-(4-fluorophenyl)pyridin-3-yl)methoxy)-2-methyl-3-(((5-methylisoxazol-3-yl)methyl)amino)-3-oxopropanoate

There total 1 articles about ethyl 2-((6-(4-fluorophenyl)pyridin-3-yl)methoxy)-2-methyl-3-(((5-methylisoxazol-3-yl)methyl)amino)-3-oxopropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 154016-48-5
(5-methyl-3-isoxazolyl)methylamine

: 1219005-60-3
3-ethoxy-2-((6-(4-fluorophenyl)pyridin3-yl)methoxy)-2-methyl-3-oxopropanoic acid

: 1219005-61-4
ethyl 2-((6-(4-fluorophenyl)pyridin-3-yl)methoxy)-2-methyl-3-(((5-methylisoxazol-3-yl)methyl)amino)-3-oxopropanoate

Guidance literature:: 3-ethoxy-2-((6-(4-fluorophenyl)pyridin3-yl)methoxy)-2-methyl-3-oxopropanoic acid; With N-ethyl-N,N-diisopropylamine; HATU; In dichloromethane; N,N-dimethyl-formamide; at 0 ℃; for 0.25h; Inert atmosphere;

(5-methyl-3-isoxazolyl)methylamine; In dichloromethane; N,N-dimethyl-formamide; at 0 - 25 ℃; Inert atmosphere;

Reference yield: 63.0%

: 1219005-61-4
ethyl 2-((6-(4-fluorophenyl)pyridin-3-yl)methoxy)-2-methyl-3-(((5-methylisoxazol-3-yl)methyl)amino)-3-oxopropanoate

: 1219004-15-5
2-((6-(4-fluorophenyl)pyridin-3-yl)methoxy)-N-hydroxy-2-methyl-N'-((5-methylisoxazol-3-yl)methyl)malonamide

Guidance literature:: ethyl 2-((6-(4-fluorophenyl)pyridin-3-yl)methoxy)-2-methyl-3-(((5-methylisoxazol-3-yl)methyl)amino)-3-oxopropanoate; With methanol; hydroxylamine hydrochloride; lithium methanolate; at 0 - 25 ℃; Inert atmosphere;

With acetic acid; In methanol; Inert atmosphere;