Hexylresorcinol

Base Information Edit

Chemical Name:Hexylresorcinol
CAS No.:136-77-6
Molecular Formula:C12H18O2
Molecular Weight:194.274
Hs Code.:29072900
European Community (EC) Number:205-257-4
NSC Number:757056,1570
UNII:R9QTB5E82N
DSSTox Substance ID:DTXSID1020699
Nikkaji Number:J2.020F
Wikipedia:Hexylresorcinol
Wikidata:Q229969
NCI Thesaurus Code:C29092
RXCUI:5321
Pharos Ligand ID:URLMZ5B2S8LG
Metabolomics Workbench ID:45612
ChEMBL ID:CHEMBL443605
Mol file:136-77-6.mol

Synonyms:4 Hexylresorcinol;4-hexylresorcinol;Hexylresorcinol

Suppliers and Price of Hexylresorcinol

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
4-Hexylresorcinol
5g
$ 305.00

TRC
p-Hexylresorcinol
2.5g
$ 95.00

TRC
p-Hexylresorcinol
1g
$ 65.00

TCI Chemical
4-Hexylresorcinol >98.0%(GC)
25g
$ 123.00

Sigma-Aldrich
4-Hexylresorcinol 98%
25g
$ 64.70

Sigma-Aldrich
4-Hexylresorcinol for synthesis
25 g
$ 79.46

Sigma-Aldrich
4-Hexylresorcinol for synthesis. CAS 136-77-6, chemical formula 4-CH (CH ) C H -1,3-(OH) ., for synthesis
8206470025
$ 83.00

Sigma-Aldrich
4-Hexylresorcinol for synthesis. CAS 136-77-6, chemical formula 4-CH (CH ) C H -1,3-(OH) ., for synthesis
8206470100
$ 160.00

Sigma-Aldrich
4-Hexylresorcinol for synthesis
100 g
$ 153.55

Sigma-Aldrich
4-Hexylresorcinol 98%
100g
$ 192.00

Total 165 raw suppliers

Chemical Property of Hexylresorcinol Edit

Chemical Property:

Appearance/Colour:slightly red powder
Vapor Pressure:0.000103mmHg at 25°C
Melting Point:65-67 °C(lit.)
Refractive Index:1.54
Boiling Point:329.5 °C at 760 mmHg
PKA:pKa 9.1 (Uncertain)
Flash Point:155.2 °C
PSA：40.46000
Density:1.049 g/cm³
LogP:3.22060
Storage Temp.:Store below +30°C.
Solubility.:chloroform: 50 mg/mL, clear
Water Solubility.:0.05 g/100 mL (18 ºC)
XLogP3:3.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:5
Exact Mass:194.130679813
Heavy Atom Count:14
Complexity:147

Purity/Quality:

99%, ^*data from raw suppliers

4-Hexylresorcinol ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 22-36/37/38-20/21/22
Safety Statements: 26-36-24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Chemical Classes:Other Classes -> Phenols
Canonical SMILES:CCCCCCC1=C(C=C(C=C1)O)O
Uses p-Hexylresorcinol shows antiimnflammatory activity acting on the human 5-LO (5-Lipoxygenase) proinflammatory enzyme. anthelmintic, topical antiseptic 4-Hexylresorcinol is an inhibitor of transglutaminase-2 in KB cells. Studies indicate that 4-Hexylresorcinol reduces DNA oxidative damage in human lymphocytes. is a substituted dihydroxybenzene used topically as an antiseptic for the treatment of minor skin infections. is a substituted phenol with bactericidal, antihelminthic and potential antineoplastic activities. The combination of 4-Hexylresorcinol and Cisplatin has been shown to inhibit tumor growth, cell growth, and KB cell viability. 4-Hexylresorcinol is used as the starting material to synthesize a potent immune suppressor, celastramycin A. It is a precursor to prepare resorcinol-sn-glycerol derivatives, that exhibit high affinity for cannabinoid type 1 receptor. It can also be incorporated as a linker while building catenanes.
Clinical Use 4-Hexylresorcinol, or “hexylresorcinol,” is a white crystallinesubstance with a faint phenolic odor. When appliedto the tongue it produces a sensation of numbness. It isfreely soluble in alcohol but only slightly soluble in water(1–20,000 parts). Hexylresorcinol is an effective antiseptic,possessing both bactericidal and fungicidal properties.The phenol coefficient of hexylresorcinol against S. aureusis 98. As is typical for alkylated phenols, hexylresorcinolpossesses surfactant properties. The compound also haslocal anesthetic activity. Hexylresorcinol is formulatedinto throat lozenges because of its local anesthetic and antisepticproperties. These preparations are probably of littlevalue. Hexylresorcinol (in the concentration in thelozenge) is probably not antiseptic, and the local anestheticproperty can anesthetize the larynx, causing temporarylaryngitis.

Technology Process of Hexylresorcinol

There total 12 articles about Hexylresorcinol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: C₁₂H₁₄O₃

: 136-77-6
4-Hexylresorcinol

Guidance literature:: With hydrogenchloride; platinum on carbon; hydrogen; In methanol; water; at 70 ℃; under 13501.4 Torr;

Reference yield: 86.2%

: 3144-54-5
4-hexanoylresorcinol

: 136-77-6
4-Hexylresorcinol

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In methanol; at 80 ℃; under 11251.1 Torr; Reagent/catalyst; Autoclave;