GlcNAc

Base Information

• Chemical Name: GlcNAc
• CAS No.: 62057-54-9
• Molecular Formula: C₈H₁₅NO₆
• Molecular Weight: 221.21
• Mol file: 62057-54-9.mol

Synonyms:GlcNAc

Chemical Property of GlcNAc

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of GlcNAc

There total 137 articles about GlcNAc which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

(+)-D-glucosamine hydrochloride (1078691-95-8) + acetic anhydride (108-24-7) → N-Acetyl-D-glucosamine (7512-17-6,72-87-7,1136-42-1,1136-44-3,6082-29-7,6730-06-9,7772-94-3,10036-64-3,14131-60-3,14131-64-7,14131-68-1,14215-68-0,62057-49-2,62057-50-5,62057-51-6,62057-52-7,62057-53-8,62057-54-9,62057-55-0,62057-56-1,62075-50-7,62137-54-6,134451-97-1,134522-12-6,148347-16-4)

Guidance literature:

With sodium hydrogencarbonate; In water; at 20 ℃; for 1.5h;

DOI:10.1002/ejoc.200300254

Reference yield:

Galβ1-4GlcNAcβ1-3Galβ1-4Glc → D-Galactose (59-23-4) + GlcNAc (62057-54-9)

Guidance literature:

With BbgIII β-galactosidase from Bifidobacterium bifidum JCM1254; BbgI β-galactosidase from Bifidobacterium bifidum JCM1254; In propan-1-ol; water; at 37 ℃; for 6h; Enzymatic reaction;

DOI:10.1093/glycob/cwq101

Reference yield:

4-nitrophenyl N-acetyl-β-D-glucosaminide (3459-18-5,50645-66-4) → 4-nitro-phenol (100-02-7,78813-13-5,89830-32-0) + N-Acetyl-D-glucosamine (7512-17-6,72-87-7,1136-42-1,1136-44-3,6082-29-7,6730-06-9,7772-94-3,10036-64-3,14131-60-3,14131-64-7,14131-68-1,14215-68-0,62057-49-2,62057-50-5,62057-51-6,62057-52-7,62057-53-8,62057-54-9,62057-55-0,62057-56-1,62075-50-7,62137-54-6,134451-97-1,134522-12-6,148347-16-4)

Guidance literature:

With chitinase from Streptomyces griseus; In phosphate buffer; at 30 ℃; for 1h; pH=6.0; Product distribution; Enzymatic reaction;

DOI:10.1016/S0008-6215(99)00002-6

upstream raw materials:

2-methyl-(1,2-dideoxy-5,6-O-isopropylidene-α-D-glucofurano)-<2,1-d>-2-oxazoline

N-acetyl neuraminic acid

uridine 5'-diphospho-N-acetylglucosamine

methanol

Downstream raw materials:

N-Acetyl-D-glucosamine

2-acetamido-2,3-dideoxy-α-D-erythro-hex-2-enofuranose

2-acetamido-3,6-anhydro-2-deoxy-β-D-mannofuranose

2-acetamido-3,6-anhydro-2-deoxy-α-D-mannofuranose