methyl 1-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-3-carboxylate

Base Information

Chemical Name:methyl 1-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-3-carboxylate
CAS No.:1616930-45-0
Molecular Formula:C₁₂H₁₉BN₂O₄
Molecular Weight:266.105
Hs Code.:

Synonyms:methyl 1-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-3-carboxylate

Suppliers and Price of methyl 1-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-3-carboxylate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 6 raw suppliers

Chemical Property of methyl 1-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-3-carboxylate

Chemical Property:

Purity/Quality:: 97% ^*data from raw suppliers

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Technology Process of methyl 1-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-3-carboxylate

There total 2 articles about methyl 1-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 17827-61-1
methyl ester of 1-methylpyrazole-3-carboxylic acid

: 25015-63-8
4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane

: 1616930-45-0
methyl 1-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-3-carboxylate

Guidance literature:: 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane; With (1,5-cyclooctadiene)(methoxy)iridium(I) dimer; 4,4'-di-tert-butyl-2,2'-bipyridine; In pentane; at 20 ℃; for 0.333333h;

methyl ester of 1-methylpyrazole-3-carboxylic acid; In tetrahydrofuran; pentane; at 20 ℃; for 72h;

Reference yield:

: 15366-34-4
methyl 1H-pyrazole 3-carboxylate

: 1616930-45-0
methyl 1-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-3-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1.1: caesium carbonate / acetonitrile / 2 h / 20 °C

2.1: 4,4'-di-tert-butyl-2,2'-bipyridine; (1,5-cyclooctadiene)(methoxy)iridium(I) dimer / pentane / 0.33 h / 20 °C

2.2: 72 h / 20 °C

With (1,5-cyclooctadiene)(methoxy)iridium(I) dimer; caesium carbonate; 4,4'-di-tert-butyl-2,2'-bipyridine; In acetonitrile; pentane;

Reference yield: 97.0%

: 1616930-45-0
methyl 1-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-3-carboxylate

: 60633-25-2
2-bromo-4-chloroanisole

: 1616930-47-2
C₁₃H₁₃ClN₂O₃

Guidance literature:: With bis(tri-t-butylphosphine)palladium⁽⁰⁾; potassium carbonate; In 1,4-dioxane; water; at 80 ℃; for 1h; Inert atmosphere;